2024-03-29T12:10:02Z
https://u-ryukyu.repo.nii.ac.jp/oai
oai:u-ryukyu.repo.nii.ac.jp:02002665
2022-02-14T21:38:57Z
1642837622505:1642837905044:1642837922297
1642838403551:1642838407312
制癌剤投与マウスにおける液性免疫応答の基礎的検討
Basal study on humoral immune responses in mice administrated with antitumor agents
上地, 俊徳
Uechi, Shuntoku
open access
マウス
溶血斑形成細胞
ヒツジ赤血球凝集素価
制癌剤
mause
plaque forming cell
HA titer
antitumor agent
In the present study the effect on the anti-SRBC antibody response in normal mice or mice that administrated with antitumor agents, mitomycin C (MMC) or cyclophosphamide (CY), has been investigated. CY was given intraperitoneally for 4 days at a does of 50 mg./kg b. w. and MMC was given intravenously for 4 days at a does 4 mg/b. w. After the administrations, spleen weight, anti-SRBC hemagglutination titer (HA) and plaque forming cell (PFC) assay were studied in these mice. Both CY and MMC, as expected, showed suppressive effects on spleen weight, HA titer in serum and PFC response in spleen.
紀要論文
琉球大学農学部
jpn
departmental bulletin paper
VoR
http://hdl.handle.net/20.500.12000/3632
http://hdl.handle.net/20.500.12000/3632
https://u-ryukyu.repo.nii.ac.jp/records/2002665
0370-4246
AN00250548
琉球大学農学部学術報告
The Science Bulletin of the Faculty of Agriculture. University of the Ryukyus
49
199
203
https://u-ryukyu.repo.nii.ac.jp/record/2002665/files/KJ00000162646.pdf