2024-03-29T12:33:17Z
https://u-ryukyu.repo.nii.ac.jp/oai
oai:u-ryukyu.repo.nii.ac.jp:02011610
2023-08-03T05:29:05Z
1642838163960:1642838338003
1642838403551:1642838407312
Effects of p-Hydroxybenzaldehyde and p-Hydroxyacetophenone from Non-centrifuged Cane Sugar, Kokuto, on Serum Corticosterone, and Liver Conditions in Chronically Stressed Mice Fed with a High-fat Diet
Kinjo, Yukiko
Wada, Koji
Oe, Moena
Hou, De-Xing
Takahashi, Makoto
open access
© 2020, Japanese Society for Food Science and Technology
antioxidant activity
anti-stress effect
hepatic lipid accumulation
non-centrifuged cane sugar
p-hydroxyacetophenone
In previous studies, the non-sugar component (NSC) fraction, analyzed as 50 % methanol extract from Kokuto, showed a high in vitro antioxidant activity and strong anti-stress effect in acutely stressed mice. In addition, p-hydroxybenzaldehyde (HBA) and p-hydroxyacetophenone (HAP) were determined to be some of the antioxidative compounds in the NSC fraction. Therefore, the aim of the present study was to investigate whether NSC fraction, HBA and HAP could suppress stress response and the changes of hepatic lipids in chronically stressed mice fed a high fat diet. The results of the present study show that the NSC fraction has a high antioxidant activity in vitro, and oral administration of the fraction and HAP suppressed the secretion of stress hormone in the chronically stressed mice. We also found that the two phenolic compounds prevented hepatic lipid accumulation and peroxidation in the stressed mice.
論文
Japanese Society for Food Science and Technology
日本食品科学工学会
2020
eng
journal article
VoR
http://hdl.handle.net/20.500.12000/48705
http://hdl.handle.net/20.500.12000/48705
https://u-ryukyu.repo.nii.ac.jp/records/2011610
https://doi.org/10.3136/fstr.26.501
https://doi.org/10.3136/fstr.26.501
1881-3984
1344-6606
Food Science and Technology Research
26
4
501
507
https://u-ryukyu.repo.nii.ac.jp/record/2011610/files/26_501.pdf