2024-03-29T06:52:49Z
https://u-ryukyu.repo.nii.ac.jp/oai
oai:u-ryukyu.repo.nii.ac.jp:02016267
2022-02-22T04:44:55Z
1642838163960:1642838198944:1642838242961:1642838249108
1642838403551:1642838412624
[原著]Allergic granulomatous angiitis の1例
A case of allergic granulomatous angiitis
大浦, 孝
河上, 好秀
山本, 誠
奥田, 治爾
Oura, Takashi
Kawakami, Yoshihide
Yamamoto, Makoto
Okuda, Koji
open access
琉球医学会
We reported a case of allergic granulomatous angiitis (AGA). A 37-year-old female patient was admitted to our clinic for closer examination of gait disturbance. She suffered from bronchial asthma for the past four years, but the attacks had ceased since the appearance of this symptom. In physical examination, her tendon reflex was depressed in the upper extremities and was absent in the lower extremities. Her grasping power was undetectable bilaterally. Sensory disturbance was apparent below the elbow and knee joints. Laboratory data indicated positive proteinuria as well as the presence of some RBC and hyaline cast in the urinary sediments. Leukocytosis was found while eosinophilia was prominent. ESR accelerated and CRP was positive. The histopathological observation of muscle biopsy revealed the presence of an inflammation around the small vessels and the prominent infiltration of eosinophils. After therapy began with the administering of adenal corticosteroid, both clinical symptoms and laboratory data showed improvement. Our cas was diagnosed as AGA which was differentiated from Periarteritis nodosa (PN) as a new clinical entity by Churg and Strauss in 1951. AGA is characterized by bronchial asthma followed by general symptoms and eosinophilia as well as, histopathologically, necrotizing angiitis and granuloma formation. This disease is so rare that only a few cases have been reported in Japan. Finally, we discussed about similar diseases related to PN.
論文
琉球大学保健学部
College of Health Sciences, University of the Ryukyus
jpn
journal article
VoR
http://hdl.handle.net/20.500.12000/0002016267
https://u-ryukyu.repo.nii.ac.jp/records/2016267
0285-9270
AN00250763
琉球大学保健学医学雑誌=Ryukyu University Journal of Health Sciences and Medicine
3
4
372
380
https://u-ryukyu.repo.nii.ac.jp/record/2016267/files/v3p372.pdf