2024-03-28T10:08:18Z
https://u-ryukyu.repo.nii.ac.jp/oai
oai:u-ryukyu.repo.nii.ac.jp:02016325
2022-02-22T04:54:50Z
1642838163960:1642838198944:1642838242961:1642838243524
1642838403551:1642838412624
[原著]Behavioral Effects of Intraspinally Injected Habu (Trimeresurus flavoviridis) Venom on Rats
Matsusaki, Kichihiko
Aniya, Yoko
open access
琉球医学会
Peng(1952) reports that Formosan cobra venom injected into the cerebellomedullary cistern of the rabbit causes a rise in blood pressure and a transient stimulation of respiration followed by a depression, and that the lethal dose is much smaller than that by the peripheral application. Bhargava et al. (1970) reveals that an application of a neurotoxic fraction prepared from Naja naja venom to the exposed cerebral cortex of the rat produces a long-lasting convulsant effect. Although histopathological changes in the central nervous system(CNS) of the cat caused by a Habu snake bite (induced experimentally) have been demonstrated by Sakae (1963), pharmacological effects of Habu venom on the CNS remain to be clarified. This investigation was made in order to study the effects of intraspinally injected Habu venom on the CNS. In an attempt to determine the mode of action of the venom on the CNS, a preliminary experiment was conducted, designed to observe whether or not formation of a pharmacologically active substance takes place under in vitro incubation of the cerebrospinal fluid (CSF) with the venom.
論文
琉球大学保健学部
College of Health Sciences, University of the Ryukyus
eng
journal article
VoR
http://hdl.handle.net/20.500.12000/0002016325
https://u-ryukyu.repo.nii.ac.jp/records/2016325
0285-9270
AN00250763
琉球大学保健学医学雑誌=Ryukyu University Journal of Health Sciences and Medicine
1
1
30
34
https://u-ryukyu.repo.nii.ac.jp/record/2016325/files/v1p30.pdf