2024-03-28T12:49:54Z
https://u-ryukyu.repo.nii.ac.jp/oai
oai:u-ryukyu.repo.nii.ac.jp:02008580
2022-10-31T04:04:49Z
1642838158423:1642838158860:1642838159351
1642838403551:1642838409905
Predictive factors of uterine movement during definitive radiotherapy for cervical cancer
子宮頸癌根治的放射線治療期間中の子宮移動の予測因子について
前本, 均
Maemoto, Hitoshi
cervical cancer
radiotherapy
computed tomography
uterus
cone-beam CT
To determine the predictive factors affecting uterine movement during radiotherapy (RT), we quantified interfraction<br/>uterine movement using computed tomography (CT) and cone-beam CT (CBCT). A total of 38 patients<br/>who underwent definitive RT for cervical cancer were retrospectively analyzed. We compared pre-RT planning CT<br/>(n = 38) and intratreatment CBCT (n = 315), measuring cervical and corporal movement in each direction. Correlations between uterine movement and volume changes of the bladder and rectum on all CBCT scans were<br/>analyzed using Spearman rank correlation analysis. Relationships between the mean uterine movement and patient<br/>factors were analyzed using the Mann–Whitney test. The mean corpus movement was: superior margin (cranio–<br/>caudal direction), 7.6 ± 5.9 mm; anterior margin (anteroposterior direction), 8.3 ± 6.3 mm; left margin (lateral direction),<br/>3.3 ± 2.9mm; and right margin (lateral direction), 3.0 ± 2.3 mm. Generally, the mean values for cervical<br/>movement were smaller than those for the corpus. There was a significant, weak correlation between changes in<br/>bladder volume and the movement of the superior margin of the corpus (ρ = 0.364, P < 0.001). There was a significant<br/>difference in movement of the superior margin of the corpus between the subgroups with and without a<br/>history of previous pelvic surgery (P = 0.007). In conclusion, change in bladder volume and a history of previous<br/>surgery were significantly related to intrafractional corpus movement; however, our observations suggest that the<br/>accurate prediction of uterine movement remains challenging.
学位論文
博士(医学)
http://purl.org/coar/resource_type/c_db06
琉球大学
University of the Ryukyus
琉球大学
2016-10-15
2017-03-24
VoR
http://hdl.handle.net/20.500.12000/36587
0449-3060
Journal of Radiation Research
8
1
甲第456号
eng
https://doi.org/10.1093/jrr/rrw101
https://doi.org/10.1093/jrr/rrw101
27744403
open access