2024-03-29T11:53:35Z
https://u-ryukyu.repo.nii.ac.jp/oai
oai:u-ryukyu.repo.nii.ac.jp:02012381
2023-08-03T05:31:13Z
1642838163960:1642838338003
1642838403551:1642838407795
Vesicovaginal/rectovaginal fistula formation and outcome of Stage IVA carcinoma of the cervix treated with radiotherapy
Kinjyo, Y.
Kudaka, W.
Toita, T.
Nakamoto, T.
Nagai, Y.
Maemoto, H.
Hashimoto, S.
Ariga, T.
Aoki, Y.
Cervical cancer
Stage IVA
Radiotherapy
Chemoradiotherapy
Vesicovaginal fistula
Rectovaginal fistula
Purpose: To review the morbidity and mortality of Stage IVA cervical cancer, with a particular focus on the incidence of fistulae. Materials and Methods: The authors retrospectively analyzed 30 patients with Stage IVA cervical cancer, treated with whole pelvic-external beam radiotherapy (WP-EBRT) and high-dose-rate intracavitary brachytherapy (HDR-ICBT). Results: Seven patients presented with vesicovaginal fistula at the time of cancer diagnosis and six developed a fistula during or after radiotherapy (RT). Fistula was diagnosed 0-41 months after cancer diagnosis. The patients with fistulae had a median survival of 32 months. Six patients are alive, four of whom have no evidence of recurrence, while two have persistent disease. The five-year overall survival (OS) was 14.9% in the patients with fistula and was 39.4% in the total series. On multivariate analysis, RT without HDR-ICBT was an independent prognostic factor. Conclusion: High rates of vesicovaginal fistulae were observed in Stage IVA cervical cancer. Interventions for vesicovaginal fistula to improve quality of life are very important.
論文
http://purl.org/coar/resource_type/c_6501
IMR PRESS
2017-12-10
VoR
http://hdl.handle.net/20.500.12000/45889
0392-2936
0392-2936
European Journal of Gynaecological Oncology
6
38
942
938
jpn
https://ejgo.imrpress.com/EN/10.12892/ejgo3701.2017
10.12892/ejgo3701.2017
open access
Creative Commons Attribution 4.0
https://creativecommons.org/licenses/by/4.0/