2024-03-28T10:27:32Z
https://u-ryukyu.repo.nii.ac.jp/oai
oai:u-ryukyu.repo.nii.ac.jp:02016145
2022-10-31T07:51:17Z
1642838163960:1642838198944:1642838199408:1642838218807
1642838403551:1642838412624
[原著]食道癌の進展特性と新しい外科治療戦略
New strategy of surgery for esophageal cancer based on the charavteristics of tumor spread and the treatment outcomes
西巻, 正
Nishimaki, Tadashi
extended radical esophagectomy
esophageal cancer
lymph node metastasis
transhiatal radical esophagectomy
micrometastasis
Extended radical esophagectomy with 3-field lymphadenectomy (3FL) has been enthusiastically performed to improve long-tem survival in patients with esophageal cancer in Japan since the early 1980s. However, some analyses of clinicopathological characteristics of long-term survivors after 3FL revealed that 3FL is indicated only for patients with four or fewer metastatic nodes or with metastases confined to one or two of the anatomic compartments (neck, mediastinum, and abdomen). Transhiatal radical esophagectomy may be adequate as a curative procedure for patients with clinically negative mediastinal metastasis from lower esophageal cancer because of the less invasiveness and equally good chances of survival as compared with 3FL. Some recent studies revealed that microtumor cells were detected in the circulating blood, bone marrow, and lymph nodes in a considerable percentage of patients at the time of diagnosis. Assessment of nodal status by both histological examination for overt metastases and immunohistchemical examination for micrometastases is useful in stratifying patients undergoing curative esophagectomy. Precise tumor staging by not only conventional but also molecular examinetions is the most important in selecting the adequate treatment modality for patients with esophageal cancer.
論文
http://purl.org/coar/resource_type/c_6501
琉球医学会
Ryukyu Medical Association
2003
VoR
1346888X
0289-1530
AN10369445
琉球医学会誌 = Ryukyu Medical Journal
1-2
22
7
1
jpn
open access
琉球医学会