2024-03-28T17:47:12Z
https://u-ryukyu.repo.nii.ac.jp/oai
oai:u-ryukyu.repo.nii.ac.jp:02019575
2022-12-06T02:36:49Z
1642838163960:1642838198944:1642838199408:1669686986892
1642838403551:1642838412624
特発性直腸穿孔術後に発症した悪性症候群の 1 例
A case of postoperative neuroleptic malignant syndrome in a patient with idiopathic perforation of the rectum
平良, 勝己
Taira, Katsumi
中山, 正彦
Nakayama, Masahiko
比嘉, 昇
Higa, Noboru
玉木, 正人
Tamaki, Masato
上里, 忠興
Uezato, Tadaoki
neuroleptic malignant syndrome
antipsychotics
peritonitis
The patient was a 47-year-old woman, who was receiving oral medication for schizophrenia and hyperthyroidism. She was diagnosed as generalized peritonitis associated with idiopathic rectal perforation and underwent the Hartmannʼs procedure. She exhibited a fever of 40℃, muscle rigidity, hypomimia, profuse sweating, and tachycardia of 130 beats / min from the 8th day of illness. Exacerbation of peritonitis was suspected, and antibiotics were administered, but no improvements were observed. Neuroleptic malignant syndrome was suspected due to a rise in creatine phosphokinase(CPK)and the suspension of orally administered antipsychotics. Upon administration of dantrolene sodium from the 10th day of illness, the patientʼs fever decreased to 36℃, and she showed improvement in general condition by the 16th day of illness. It was difficult to distinguish between residual abscesses after generalized peritonitis and neuroleptic malignant syndrome as the cause of persistent fever. However, we report on this case, with some literature review, since the patient experienced malignant syndrome, which developed after idiopathic rectal perforation, that was treated by the use of dantrolene sodium.
http://purl.org/coar/resource_type/c_6501
琉球医学会
2021-10
VoR
1346-888X
AN10369445
琉球医学会誌 = Ryukyu Medical Journal
1-4
40
53
47
jpn
open access
琉球医学会