{"created":"2022-01-27T02:14:34.780411+00:00","id":2002037,"links":{},"metadata":{"_buckets":{"deposit":"f19104b2-9d9d-4a47-af1c-8e1d527e3e40"},"_deposit":{"id":"2002037","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2002037"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02002037","sets":["1642837622505:1642837745608:1642837756633","1642838403551:1642838405037"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"A STUDY ON THE QUATERNARY STRUCTURE CHANGE OF HEMOGLOBIN I. INTERMEDIATE STRUCTURES IN O_2 LIGATION PROCESS","subitem_1551255648112":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Arata, Yasuhide","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yara, Asao","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"\u65b0\u7530, \u4fdd\u79c0","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"\u5c4b\u826f, \u671d\u592b","creatorNameLang":"ja"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Conformational interaction at the interfaces between subunits are investigated on the basis of the atomic coordinates of human deoxy and human oxy Hbs. Hypothetical intermediate structures are used, each of which is obtained from the procedure where one or more subunits in deoxy Hb are replaced by the corresponding O_2-liganded subunits in oxy Hb using the method of superimposition of two sets of atomic coordinates. When either \u03b1 or \u03b2 subunit is substituted with the corresponding subunit in oxy Hb, serious steric hindrances are produced between \u03b1_1FG 4(92)Arg and \u03b2_2C 3(37)Trp or between \u03b1_1C 6(41)Thr and \u03b2_2FG 4(97)His, all of which belong to the allosteric core affected directly by ligand binding. These steric hindrances become more serious when both \u03b1_1(\u03b1_2) and \u03b2_2 (\u03b2_1) subunits are substituted. However, no steric hindrance can be seen between subunits when the subunits in oxy Hb are substituted with the corresponding subunits in deoxy Hb.","subitem_description_type":"Other"},{"subitem_description":"\u7d00\u8981\u8ad6\u6587","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"\u7409\u7403\u5927\u5b66\u6559\u80b2\u5b66\u90e8"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"eng"}]},"item_1617186783814":{"attribute_name":"Identifier","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/20.500.12000/1873"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"0386-5746"},{"subitem_1522646500366":"NCID","subitem_1522646572813":"AN10144831"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"\u7409\u7403\u5927\u5b66\u6559\u80b2\u5b66\u90e8\u7d00\u8981 \u7b2c\u4e00\u90e8\u30fb\u7b2c\u4e8c\u90e8"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueNumber":"34","bibliographicPageEnd":"257","bibliographicPageStart":"247"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"Vol34p247.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2002037/files/Vol34p247.pdf"},"version_id":"d62a4052-78d3-4c12-bc02-a2e02ff1560a"}]},"item_title":"A STUDY ON THE QUATERNARY STRUCTURE CHANGE OF HEMOGLOBIN I. INTERMEDIATE STRUCTURES IN O_2 LIGATION PROCESS","item_type_id":"15","owner":"1","path":["1642837756633","1642838405037"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-09-15"},"publish_date":"2007-09-15","publish_status":"0","recid":"2002037","relation_version_is_last":true,"title":["A STUDY ON THE QUATERNARY STRUCTURE CHANGE OF HEMOGLOBIN I. INTERMEDIATE STRUCTURES IN O_2 LIGATION PROCESS"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-02-14T21:22:08.776973+00:00"}