@article{oai:u-ryukyu.repo.nii.ac.jp:02002951,
 author = {多和田, 真吉 and 本郷, 富士弥 and 砂川, 勝徳 and 川島, 由次 and 屋我, 嗣良 and Tawata, Shinkichi and Hongo, Fujiya and Sunagawa, Katsunori and Kawashima, Yoshitugu and Yaga, Shiryo},
 issue = {33},
 journal = {琉球大学農学部学術報告, The Science Bulletin of the Faculty of Agriculture. University of the Ryukyus},
 month = {Dec},
 note = {ギンネム(Leucaena leucocephala de Wit)中には,ミモシン(β-〔N-(3-hydroxy pyridone-4)-α-aminopropionic acid)が存在するため, 動物がそれを摂取すると脱毛症, 成長障害, 白内障, 不妊症などを引き起こす。ミモシンの分解産物3-hydroxy-4(IH)-pyridone(DHP)もまた動物に甲状腺腫誘発性があると報告されている。飼料として調製中あるいは調製前にギンネム中のミモシンおよびDHPを不活性化あるいは除去できるのならば,家畜飼料のタンパク源としてギンネムの利用が大きく高揚するだろう。精製ミモシンは蒸留水には難溶性であるが, イオン性溶液には易溶性を示した。ミモシン茎葉部を0∿100%海水あるいは酸類, 塩類の各種濃度液に25℃で24時間浸漬すると, およそ60∿95%のミモシンが溶脱された。ギンネムからのミモシンの溶脱率は試薬の濃度に左右され, 最も効果的なものは0.05N CH_3-COONaで95%ものミモシンが抽出される事がわかった。家畜飼料として利用するのに重要な栄養源である粗脂肪, 粗組織, 粗タンパク質の損失はほとんどなかった。この方法は比較的簡単であり, ミモシンもDHPも同時に除去する事から, 農家における小規模な処理法から, 企業による大規模生産まで応用できる実用的な方法であると思われた。, Because of the presence of mimosine (β-[N-(3-hydroxypyridone-4)-α-amino-propionic acid) in leucaena (Leucaena leucocephala de Wit), the ingestion of the plant by animals causes alopecia, growth retardation, cataract and infertility. The mimosine degradation product 3-hydroxy-4(1H)-pyridone (DHP) is also reported to be goitrogenic in animals. Inactivation or reduction of mimosine and DHP in the plant before or during the preparation of the plant as feed would enhance the use of the legume as a source of protein for livestock feed. Although purified mimosine is not soluble in distilled water, it become very soluble in the ionic solutions. When the leaves of leucaena were leached in 0∿100% sea water or in various concentrations of acids and bases for 24 hrs at 25℃, about 60∿95% of the mimosine was extracted. As the rate of mimosine extraction from the leaf of leucaena depended on the concentration of reagents, it was found that 0.05N CH_3COONa was the most effective at extracting 95% of the mimosine. There were no loss of the nutrients, important for use as a livestock feed, such as crude fat, crude fiber and crude protein. The method is relatively simple and removes simultaneously both mimosine and DHP, therefore, it is beleaved to be a method practically applicable for both the small scale treatment of a local farmer and the large scale treatment of a commercial enterprise., 紀要論文},
 pages = {87--94},
 title = {熱帯植物ギンネム中のミモシンの簡易除去法(農芸化学科)},
 year = {1986}
}