ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "117e1404-ddad-46c7-a466-9f646b47baef"}, "_deposit": {"id": "2007278", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "2007278"}, "status": "published"}, "_oai": {"id": "oai:u-ryukyu.repo.nii.ac.jp:02007278", "sets": ["1642838159351", "1642838409905"]}, "author_link": [], "item_1617186331708": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "\u5727\u8feb\u306b\u3088\u308b\u8133\u969c\u5bb3\u306b\u95a2\u3059\u308b\u57fa\u790e\u7684\u7814\u7a76", "subitem_1551255648112": "ja"}, {"subitem_1551255647225": "Experimental study on brain damage by extracerebral compression", "subitem_1551255648112": "en"}]}, "item_1617186419668": {"attribute_name": "Creator", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u4f50\u4e45\u7530, \u6cbb", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "Sakuta, Osamu", "creatorNameLang": "en"}]}]}, "item_1617186476635": {"attribute_name": "Access Rights", "attribute_value_mlt": [{"subitem_1522299639480": "open access", "subitem_1600958577026": "http://purl.org/coar/access_right/c_abf2"}]}, "item_1617186609386": {"attribute_name": "Subject", "attribute_value_mlt": [{"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "extracerebral compression"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "intracranial pressure"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "histology"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "brain atrophy"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "chromatolysis"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "cerebral circulation"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "angioarchitecture"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "scanning electron microscope"}]}, "item_1617186626617": {"attribute_name": "Description", "attribute_value_mlt": [{"subitem_description": "\u5831\u544a\u756a\u53f7(\u7532\u7b2c3\u53f7)", "subitem_description_type": "Other"}, {"subitem_description": "(Abstract 1)The effects of long-standing brain compression were investigated in 26 adult cats. Brain compression was produced by inserting 12 steel balls (5mm in diameter, at 10 minute intervals) into extradural space through a small bur hole in the left temporal bone. The animals were divided into six groups according to the compression period (1 hr, 6 hrs, 2 days, 7 days, 1 month and 6 months). In 10 cats of the 1 hr and 6 hr group, mean arterial blood pressure and intracranial pressure (ICP) were monitored during brain compression. Maximum distanc of midline shift (MS) and hemispheric area ratio (HAR), an index of the volume of the compressed hemisphere, were calculated and histological evaluation was made in detail. ICP progressively increased up to 30mmHg during ball insertion, but it returned to normal level within 6 hours. HAR showed marked reduction in the 1 and 6 month groups. Histologically, chromatolysis, degenaration of neurons and infiltration of microglia were found in the compressed cortex in the 2 day to 6 month groups. Gliosis and destruction of cortical architecture were found in the 1 and 6 month groups. These data shovv that intracranial mass causes prograssive atrophy of the brain tissue. Chromatolysis seems to be a major findin in the brain sustaining long-standing compression and it followed by severe degenaration of neurons and destruction of cortical architecture. Brain atrophy become apparent within 1 month of compression. These findings suggest that brain compression by intracranial mass must be removed within 1 month in order to avoid further brain tissue damage.", "subitem_description_type": "Other"}, {"subitem_description": "(Abstract 2)Effects of extracerebral compression on cerebral circulation and microvascular architecture were investigated in 23 adult cats. Brain compression was produced by inserting 12 steel balls (5 mm in diameter, at 10 minute intervals) into the extradural space through a burr hole in the left temporal bone. Mean arterial blood pressure (MABP), intracranial pressure (ICP) and cerebral blood flow (CBF) were measured continuously. Cerebral perfusion pressure (CPP) and cerebrovascular resistance (CVR) were then calculated. Microvascular architecture of he brain was studied by scanning electron microscope (SEM) in the cerebrovascular casting methods. CBF decreased significantly on the compressed side though CPP remained unchanged untili the insertion of 5th ball. CVR increased correlatively to the number of balls on the compressed side while it remained unchanged on the contralateral side. In SEM study, flexion and interruption of capillaries and the crossing and pressing phenomenon of the pial vessels were most remarkable in the compressed side. The degree of alteration in the microvascular architectures corresponds to the structural shift of the brain. These data show that increase of CVR correlating to alteration of microvascular architectures plays an important role in decrease of CBF in a compressed brain. It is suggested that intracranial mass lesions causing structural shift of brain must be removed in order to avoid further brain tissue damage due to microvascular lesions.", "subitem_description_type": "Other"}, {"subitem_description": "\u7b2c1\u5831. \u9577\u671f\u5727\u8feb\u306b\u3088\u308b\u8133\u840e\u7e2e\u306e\u5f62\u6210\u904e\u7a0b\u306b\u3064\u3044\u3066", "subitem_description_type": "TableOfContents"}, {"subitem_description": "\u7b2c2\u5831. \u8133\u5faa\u74b0\u3068\u5fae\u5c0f\u8840\u7ba1\u69cb\u7bc9\u306e\u5909\u5316", "subitem_description_type": "TableOfContents"}, {"subitem_description": "\u5b66\u4f4d\u8ad6\u6587", "subitem_description_type": "Other"}]}, "item_1617186643794": {"attribute_name": "Publisher", "attribute_value_mlt": [{"subitem_1522300295150": "ja", "subitem_1522300316516": "\u4f50\u4e45\u7530\u6cbb"}]}, "item_1617186702042": {"attribute_name": "Language", "attribute_value_mlt": [{"subitem_1551255818386": "jpn"}]}, "item_1617186783814": {"attribute_name": "Identifier", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/20.500.12000/25395"}]}, "item_1617187056579": {"attribute_name": "Bibliographic Information", "attribute_value_mlt": [{"bibliographicPageEnd": "37", "bibliographicPageStart": "1"}]}, "item_1617187112279": {"attribute_name": "Degree Name", "attribute_value_mlt": [{"subitem_1551256126428": "\u533b\u5b66\u535a\u58eb", "subitem_1551256129013": "ja"}]}, "item_1617187136212": {"attribute_name": "Date Granted", "attribute_value_mlt": [{"subitem_1551256096004": "1991-03-22"}]}, "item_1617258105262": {"attribute_name": "Resource Type", "attribute_value_mlt": [{"resourcetype": "doctoral thesis", "resourceuri": "http://purl.org/coar/resource_type/c_db06"}]}, "item_1617265215918": {"attribute_name": "Version Type", "attribute_value_mlt": [{"subitem_1522305645492": "VoR", "subitem_1600292170262": "http://purl.org/coar/version/c_970fb48d4fbd8a85"}]}, "item_1617605131499": {"attribute_name": "File", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "download_preview_message": "", "file_order": 0, "filename": "000000410206-2.pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "", "size": 0, "url": {"objectType": "fulltext", "url": "https://u-ryukyu.repo.nii.ac.jp/record/2007278/files/000000410206-2.pdf"}, "version_id": "0a0246fd-11c9-432d-8659-f9f81b1029e2"}, {"accessrole": "open_access", "download_preview_message": "", "file_order": 1, "filename": "000000410206-1.pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "", "size": 0, "url": {"objectType": "fulltext", "url": "https://u-ryukyu.repo.nii.ac.jp/record/2007278/files/000000410206-1.pdf"}, "version_id": "0a58788a-7ceb-4c22-8048-1c0ac94ee91e"}]}, "item_1617944105607": {"attribute_name": "Degree Grantor", "attribute_value_mlt": [{"subitem_1551256015892": [{"subitem_1551256027296": "18001", "subitem_1551256029891": "kakenhi"}], "subitem_1551256037922": [{"subitem_1551256042287": "\u7409\u7403\u5927\u5b66", "subitem_1551256047619": "ja"}]}]}, "item_title": "\u5727\u8feb\u306b\u3088\u308b\u8133\u969c\u5bb3\u306b\u95a2\u3059\u308b\u57fa\u790e\u7684\u7814\u7a76", "item_type_id": "15", "owner": "1", "path": ["1642838159351", "1642838409905"], "permalink_uri": "http://hdl.handle.net/20.500.12000/25395", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2021-12-15"}, "publish_date": "2021-12-15", "publish_status": "0", "recid": "2007278", "relation": {}, "relation_version_is_last": true, "title": ["\u5727\u8feb\u306b\u3088\u308b\u8133\u969c\u5bb3\u306b\u95a2\u3059\u308b\u57fa\u790e\u7684\u7814\u7a76"], "weko_shared_id": -1}
  1. 学位論文
  2. 博士論文
  3. 医学研究科
  1. 部局別インデックス
  2. 医学研究科

圧迫による脳障害に関する基礎的研究

http://hdl.handle.net/20.500.12000/25395
http://hdl.handle.net/20.500.12000/25395
f1c2ce4c-c74c-4bb7-a422-1f2cc4a9542d
名前 / ファイル ライセンス アクション
000000410206-2.pdf 000000410206-2.pdf
000000410206-1.pdf 000000410206-1.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2021-12-15
タイトル
タイトル 圧迫による脳障害に関する基礎的研究
言語 ja
作成者 佐久田, 治

× 佐久田, 治

ja 佐久田, 治

Sakuta, Osamu

× Sakuta, Osamu

en Sakuta, Osamu

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
主題
言語 en
主題Scheme Other
主題 extracerebral compression
言語 en
主題Scheme Other
主題 intracranial pressure
言語 en
主題Scheme Other
主題 histology
言語 en
主題Scheme Other
主題 brain atrophy
言語 en
主題Scheme Other
主題 chromatolysis
言語 en
主題Scheme Other
主題 cerebral circulation
言語 en
主題Scheme Other
主題 angioarchitecture
言語 en
主題Scheme Other
主題 scanning electron microscope
内容記述
内容記述タイプ Other
内容記述 報告番号(甲第3号)
内容記述タイプ Other
内容記述 (Abstract 1)The effects of long-standing brain compression were investigated in 26 adult cats. Brain compression was produced by inserting 12 steel balls (5mm in diameter, at 10 minute intervals) into extradural space through a small bur hole in the left temporal bone. The animals were divided into six groups according to the compression period (1 hr, 6 hrs, 2 days, 7 days, 1 month and 6 months). In 10 cats of the 1 hr and 6 hr group, mean arterial blood pressure and intracranial pressure (ICP) were monitored during brain compression. Maximum distanc of midline shift (MS) and hemispheric area ratio (HAR), an index of the volume of the compressed hemisphere, were calculated and histological evaluation was made in detail. ICP progressively increased up to 30mmHg during ball insertion, but it returned to normal level within 6 hours. HAR showed marked reduction in the 1 and 6 month groups. Histologically, chromatolysis, degenaration of neurons and infiltration of microglia were found in the compressed cortex in the 2 day to 6 month groups. Gliosis and destruction of cortical architecture were found in the 1 and 6 month groups. These data shovv that intracranial mass causes prograssive atrophy of the brain tissue. Chromatolysis seems to be a major findin in the brain sustaining long-standing compression and it followed by severe degenaration of neurons and destruction of cortical architecture. Brain atrophy become apparent within 1 month of compression. These findings suggest that brain compression by intracranial mass must be removed within 1 month in order to avoid further brain tissue damage.
内容記述タイプ Other
内容記述 (Abstract 2)Effects of extracerebral compression on cerebral circulation and microvascular architecture were investigated in 23 adult cats. Brain compression was produced by inserting 12 steel balls (5 mm in diameter, at 10 minute intervals) into the extradural space through a burr hole in the left temporal bone. Mean arterial blood pressure (MABP), intracranial pressure (ICP) and cerebral blood flow (CBF) were measured continuously. Cerebral perfusion pressure (CPP) and cerebrovascular resistance (CVR) were then calculated. Microvascular architecture of he brain was studied by scanning electron microscope (SEM) in the cerebrovascular casting methods. CBF decreased significantly on the compressed side though CPP remained unchanged untili the insertion of 5th ball. CVR increased correlatively to the number of balls on the compressed side while it remained unchanged on the contralateral side. In SEM study, flexion and interruption of capillaries and the crossing and pressing phenomenon of the pial vessels were most remarkable in the compressed side. The degree of alteration in the microvascular architectures corresponds to the structural shift of the brain. These data show that increase of CVR correlating to alteration of microvascular architectures plays an important role in decrease of CBF in a compressed brain. It is suggested that intracranial mass lesions causing structural shift of brain must be removed in order to avoid further brain tissue damage due to microvascular lesions.
内容記述タイプ TableOfContents
内容記述 第1報. 長期圧迫による脳萎縮の形成過程について
内容記述タイプ TableOfContents
内容記述 第2報. 脳循環と微小血管構築の変化
内容記述タイプ Other
内容記述 学位論文
出版者
言語 ja
出版者 佐久田治
言語
言語 jpn
資源タイプ
資源タイプ doctoral thesis
資源タイプ識別子 http://purl.org/coar/resource_type/c_db06
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/25395
識別子タイプ HDL
書誌情報
p. 1-37
学位名
学位名 医学博士
言語 ja
学位授与年月日
学位授与年月日 1991-03-22
学位授与機関
学位授与機関識別子
学位授与機関識別子 18001
学位授与機関識別子Scheme kakenhi
学位授与機関名
学位授与機関名 琉球大学
言語 ja
戻る
0
views
See details
Views

Versions

Ver.1 2022-01-28 04:17:47.544604
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON

確認


Powered by WEKO3


Powered by WEKO3