{"created":"2022-02-01T05:36:26.093769+00:00","id":2011043,"links":{},"metadata":{"_buckets":{"deposit":"bada00fc-205a-4788-bf22-ae81215a3c80"},"_deposit":{"id":"2011043","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2011043"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02011043","sets":["1642838163960:1642838338003","1642838403551:1642838407795"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"Fine-Scale Genetic Structure and Demographic History in the Miyako Islands of the Ryukyu Archipelago","subitem_1551255648112":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Matsunami, Masatoshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Koganebuchi, Kae","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Imamura, Minako","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ishida, Hajime","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kimura, Ryosuke","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Maeda, Shiro","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_1522650717957":"ja","subitem_1522651041219":"© The Author(s) 2021"},{"subitem_1522650717957":"en","subitem_1522651041219":"Creative Commons Attribution 4.0"},{"subitem_1522650717957":"en","subitem_1522650727486":"https://creativecommons.org/licenses/by/4.0/","subitem_1522651041219":"https://creativecommons.org/licenses/by/4.0/"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"Ryukyu archipelago"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"biobank"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"Japanese"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"insular biogeography"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"population structure"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"demographic history"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"The Ryukyu Archipelago is located in the southwest of the Japanese islands and is composed of dozens of islands, grouped into the Miyako Islands, Yaeyama Islands, and Okinawa Islands. Based on the results of principal component analysis on genome-wide single-nucleotide polymorphisms, genetic differentiation was observed among the island groups of the Ryukyu Archipelago. However, a detailed population structure analysis of the Ryukyu Archipelago has not yet been completed. We obtained genomic DNA samples from 1,240 individuals living in the Miyako Islands, and we genotyped 665,326 single-nucleotide polymorphisms to infer population history within the Miyako Islands, including Miyakojima, Irabu, and Ikema islands. The haplotype-based analysis showed that populations in the Miyako Islands were divided into three subpopulations located on Miyakojima northeast, Miyakojima southwest, and Irabu/Ikema. The results of haplotype sharing and the D statistics analyses showed that the Irabu/Ikema subpopulation received gene flows different from those of the Miyakojima subpopulations, which may be related with the historically attested immigration during the Gusuku period (900 − 500 BP). A coalescent-based demographic inference suggests that the Irabu/Ikema population firstly split away from the ancestral Ryukyu population about 41 generations ago, followed by a split of the Miyako southwest population from the ancestral Ryukyu population (about 16 generations ago), and the differentiation of the ancestral Ryukyu population into two populations (Miyako northeast and Okinawajima populations) about seven generations ago. Such genetic information is useful for explaining the population history of modern Miyako people and must be taken into account when performing disease association studies.","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"en","subitem_1522300316516":"Oxford University Press"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"eng"}]},"item_1617186783814":{"attribute_name":"Identifier","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/20.500.12000/50049"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"0737-4038"},{"subitem_1522646500366":"ISSN","subitem_1522646572813":"1537-1719"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"en","subitem_1522650091861":"Molecular Biology and Evolution"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"2056","bibliographicPageStart":"2045","bibliographicVolumeNumber":"38"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_1522306287251":{"subitem_1522306382014":"DOI","subitem_1522306436033":"https://doi.org/10.1093/molbev/msab005"}},{"subitem_1522306287251":{"subitem_1522306382014":"DOI","subitem_1522306436033":"https://doi.org/10.1093/molbev/msab005"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"msab005.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2011043/files/msab005.pdf"},"version_id":"8239dd7a-0d4f-41ef-8027-da9546c2b619"}]},"item_title":"Fine-Scale Genetic Structure and Demographic History in the Miyako Islands of the Ryukyu Archipelago","item_type_id":"15","owner":"1","path":["1642838338003","1642838407795"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-11-17"},"publish_date":"2021-11-17","publish_status":"0","recid":"2011043","relation_version_is_last":true,"title":["Fine-Scale Genetic Structure and Demographic History in the Miyako Islands of the Ryukyu Archipelago"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-08-03T05:33:06.329255+00:00"}