@article{oai:u-ryukyu.repo.nii.ac.jp:02011106,
 author = {Imamura, Minako and Takahashi, Atsushi and Yamauchi, Toshimasa and Hara, Kazuo and Yasuda, Kazuki and Grarup, Niels and Zhao, Wei and Wang, Xu and Huerta-Chagoya, Alicia and Hu, Cheng and Moon, Sanghoon and Long, Jirong and Kwak, Soo Heon and Rasheed, Asif and Saxena, Richa and Ma, Ronald C. W. and Okada, Yukinori and Iwata, Minoru and Hosoe, Jun and Shojima, Nobuhiro and Iwasaki, Minaka and Fujita, Hayato and Suzuki, Ken and Danesh, John and Jorgensen, Torben and Jorgensen, Marit E. and Witte, Daniel R. and Brandslund, Ivan and Christensen, Cramer and Hansen, Torben and Mercader, Josep M. and Flannick, Jason and Moreno-Macias, Hortensia and Burtt, Noel P. and Zhang, Rong and Kim, Young Jin and Zheng, Wei and Singh, Jai Rup and Tam, Claudia H. T. and Hirose, Hiroshi and Maegawa, Hiroshi and Ito, Chikako and Kaku, Kohei and Watada, Hirotaka and Tanaka, Yasushi and Tobe, Kazuyuki and Kawamori, Ryuzo and Kubo, Michiaki and Cho, Yoon Shin and Chan, Juliana C. N. and Sanghera, Dharambir and Frossard, Philippe and Park, Kyong Soo and Shu, Xiao-Ou and Kim, Bong-Jo and Florez, Jose C. and Tusie-Luna, Teresa and Jia, Weiping and Tai, E. Shyong and Pedersen, Oluf and Saleheen, Danish and Maeda, Shiro and Kadowaki, Takashi},
 journal = {Nature Communications},
 month = {Jan},
 note = {Genome-wide association studies (GWAS) have identified more than 80 susceptibility loci for type 2 diabetes (T2D), but most of its heritability still remains to be elucidated. In this study, we conducted a meta-analysis of GWAS for T2D in the Japanese population. Combined data from discovery and subsequent validation analyses (23,399 T2D cases and 31,722 controls) identify 7 new loci with genome-wide significance (P<5 x 10^<-8>), rs1116357 near CCDC85A, rs147538848 in FAM60A, rs1575972 near DMRTA1, rs9309245 near ASB3, rs67156297 near ATP8B2, rs7107784 near MIR4686 and rs67839313 near INAFM2. Of these, the association of 4 loci with T2D is replicated in multi-ethnic populations other than Japanese (up to 65,936 T2Ds and 158,030 controls, P<0.007). These results indicate that expansion of single ethnic GWAS is still useful to identify novel susceptibility loci to complex traits not only for ethnicity-specific loci but also for common loci across different ethnicities., 論文},
 title = {Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes},
 volume = {7},
 year = {2016}
}