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  1. 学術雑誌論文
  2. その他
  1. 部局別インデックス
  2. 医学部

Admixture and natural selection shaped genomes of an Austronesian-speaking population in the Solomon Islands

http://hdl.handle.net/20.500.12000/46968
http://hdl.handle.net/20.500.12000/46968
90a02dcc-9b23-4cd0-8adf-ed9607dde110
名前 / ファイル ライセンス アクション
s41598-020-62866-3.pdf s41598-020-62866-3.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2020-10-13
タイトル
タイトル Admixture and natural selection shaped genomes of an Austronesian-speaking population in the Solomon Islands
言語 en
作成者 Isshiki, Mariko

× Isshiki, Mariko

en Isshiki, Mariko

Naka, Izumi

× Naka, Izumi

en Naka, Izumi

Watanabe, Yusuke

× Watanabe, Yusuke

en Watanabe, Yusuke

Nishida, Nao

× Nishida, Nao

en Nishida, Nao

Kimura, Ryosuke

× Kimura, Ryosuke

en Kimura, Ryosuke

Furusawa, Takuro

× Furusawa, Takuro

en Furusawa, Takuro

Natsuhara, Kazumi

× Natsuhara, Kazumi

en Natsuhara, Kazumi

Yamauchi, Taro

× Yamauchi, Taro

en Yamauchi, Taro

Nakazawa, Minato

× Nakazawa, Minato

en Nakazawa, Minato

Ishida, Takafumi

× Ishida, Takafumi

en Ishida, Takafumi

Eddie, Ricky

× Eddie, Ricky

en Eddie, Ricky

Ohtsuka, Ryutaro

× Ohtsuka, Ryutaro

en Ohtsuka, Ryutaro

Ohashi, Jun

× Ohashi, Jun

en Ohashi, Jun

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 en
権利情報 Creative Commons Attribution 4.0
言語 en
権利情報Resource https://creativecommons.org/licenses/by/4.0/
権利情報 https://creativecommons.org/licenses/by/4.0/
内容記述
内容記述タイプ Other
内容記述 People in the Solomon Islands today are considered to have derived from Asian- and Papuan-related ancestors. Papuan-related ancestors colonized Near Oceania about 47,000 years ago, and Asian-related ancestors were Austronesian (AN)-speaking population, called Lapita, who migrated from Southeast Asia about 3,500 years ago. These two ancestral populations admixed in Near Oceania before the expansion of Lapita people into Remote Oceania. To understand the impact of the admixture on the adaptation of AN-speaking Melanesians in Near Oceania, we performed the genome-wide single nucleotide polymorphism (SNP) analysis of 21 individuals from Munda, the main town of the New Georgia Islands in the western Solomon Islands. Population samples from Munda were genetically similar to other Solomon Island population samples. The analysis of genetic contribution from the two different ancestries to the Munda genome revealed significantly higher proportions of Asian- and Papuan-related ancestries in the region containing the annexin A1 (ANXA1) gene (Asian component > 82.6%) and in the human leukocyte antigen (HLA) class II region (Papuan component > 85.4%), respectively. These regions were suspected to have undergone natural selection since the time of admixture. Our results suggest that admixture had affected adaptation of AN-speaking Melanesians in the Solomon Islands.
内容記述タイプ Other
内容記述 論文
出版者
言語 en
出版者 Springer Nature
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/46968
識別子タイプ HDL
関連情報
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1038/s41598-020-62866-3
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1038/s41598-020-62866-3
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 2045-2322
収録物名
言語 en
収録物名 Scientific Reports
書誌情報
巻 10, 号 1
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