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  1. 学術雑誌論文
  2. その他
  1. 部局別インデックス
  2. 医学部

Cerebellar Contribution to Pattern Separation of Human Hippocampal Memory Circuits

http://hdl.handle.net/20.500.12000/47627
http://hdl.handle.net/20.500.12000/47627
49141cc0-a406-46de-90b0-17f240a7117f
名前 / ファイル ライセンス アクション
Shiroma2016_Article_CerebellarContributionToPatter.pdf Shiroma2016_Article_CerebellarContributionToPatter.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2021-01-04
タイトル
タイトル Cerebellar Contribution to Pattern Separation of Human Hippocampal Memory Circuits
言語 en
作成者 Shiroma, Ayano

× Shiroma, Ayano

en Shiroma, Ayano

Nishimura, Masahiko

× Nishimura, Masahiko

en Nishimura, Masahiko

Nagamine, Hideki

× Nagamine, Hideki

en Nagamine, Hideki

Miyagi, Tomohisa

× Miyagi, Tomohisa

en Miyagi, Tomohisa

Hokama, Yohei

× Hokama, Yohei

en Hokama, Yohei

Watanabe, Takashi

× Watanabe, Takashi

en Watanabe, Takashi

Murayama, Sadayuki

× Murayama, Sadayuki

en Murayama, Sadayuki

Tsutsui, Masato

× Tsutsui, Masato

en Tsutsui, Masato

Tominaga, Daisuke

× Tominaga, Daisuke

en Tominaga, Daisuke

Ishiuchi, Shogo

× Ishiuchi, Shogo

en Ishiuchi, Shogo

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 en
権利情報 Creative Commons Attribution 4.0
言語 en
権利情報Resource http://creativecommons.org/licenses/by/4.0/
権利情報 http://creativecommons.org/licenses/by/4.0/
主題
言語 en
主題Scheme Other
主題 Posterior lateral cerebellum
言語 en
主題Scheme Other
主題 Cognitive function
言語 en
主題Scheme Other
主題 Brain tumor
言語 en
主題Scheme Other
主題 Memory
言語 en
主題Scheme Other
主題 Hippocampus
言語 en
主題Scheme Other
主題 fMRI
内容記述
内容記述タイプ Other
内容記述 The cerebellum is a crucial structure for cognitive function as well as motor control. Benign brain tumors such as schwannomas, meningiomas, and epidermoids tend to occur in the cerebellopontine angle cisterns and may cause compression of the posterior lateral cerebellum near the superior posterior fissure, where the eloquent area for cognitive function was recently identified. The present study examined cognitive impairment in patients with benign cerebellar tumors before and after surgical intervention in order to clarify the functional implications of this region in humans. Patients with cerebellar tumors showed deficits in psychomotor speed and working memory compared with healthy controls. Moreover, these impairments were more pronounced in patients with right cerebellar tumors. Functional magnetic resonance imaging during performance of a lure task also demonstrated that cerebellar tumors affected pattern separation or the ability to distinguish similar experiences of episodic memory or events with discrete, non-overlapping representations, which is one of the important cognitive functions related to the hippocampus. The present findings indicate that compression of the human posterior lateral cerebellum affects hippocampal memory function.
内容記述タイプ Other
内容記述 論文
出版者
言語 en
出版者 Springer
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/47627
識別子タイプ HDL
関連情報
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1007/s12311-015-0726-0
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1007/s12311-015-0726-0
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1473-4222
収録物識別子タイプ ISSN
収録物識別子 1473-4230
収録物名
言語 en
収録物名 Cerebellum
書誌情報
巻 15, 号 6, p. 645-662
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