{"created":"2022-02-01T06:42:19.897676+00:00","id":2011336,"links":{},"metadata":{"_buckets":{"deposit":"0008de9e-2c55-4f2f-b897-34d1b8e08393"},"_deposit":{"id":"2011336","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2011336"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02011336","sets":["1642838163960:1642838338003","1642838403551:1642838407795"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"強皮症様皮膚硬化を認める難治性慢性GVHDに対し短波長紫外線照射が奏功した4症例","subitem_1551255648112":"ja"},{"subitem_1551255647225":"Efficacy of narrowband UV-B phototherapy for pediatric restrictive sclerodermatous chronic graft-versus host dsease (GVHD) : a report of 4 cases from a single institute","subitem_1551255648112":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"浜田, 聡","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"宮下, 倫江","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"山本, 雄一","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"宮本, 二郎","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"屋冝, 孟","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"大城, 登喜子","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"浜田, 有為子","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"喜友名, しのぶ","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"新垣, 真弓","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"百名, 伸之","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"Hamada, Satoru","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Miyashita, Michie","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yamamoto, Yuichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Miyamoto, Jiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yagi, Takeshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Oshiro, Tokiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Hamada, Yuiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kiyuna, Shinobu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Arakaki, Mayumi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Hyakuna, Nobuyuki","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_1522650717957":"ja","subitem_1522651041219":"© 2016 日本小児血液・がん学会"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"sclerodermatous graft-versus-host disease"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"narrowband UV-B"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"joint contracture"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Sclerodermatous GVHD is a late effect of hematopoietic stem cell transplantation, which results in the impairment of the quality of a ­survivor’s life, and is difficult to manage. Most cases are often steroid-refractory and steroid-dependent sclerodermatous GVHD, and secondary treatment sometimes has limited efficacy. We performed a retrospective study on four sclerodermatous GVHD patients presenting severe joint contracture treated with narrow-band ultraviolet B (NB-UVB) from July 2012 to May 2015. All the patients had sclerodermatous grade 2 or higher according to the National Institutes of Health (NIH) grading, and showed less than 70% in the performance scale (PS). Three patients received steroid therapy, namely, two patients with steroid-refractory and one patient with steroiddependent sclerodermatous GVHD. The remaining patient had a high possibility of acute myeloid leukemia relapse, favoring less immuno­suppressant administration. We evaluated the responses of the patients with a photographic range of motion according to the NIH therapeutic response criteria. The observation period after irradiation was 718 days (range: 368–1039 days). A mean cumulative dose of 75 J/cm^2  (range: 51–221 J/cm^2 ) was applied in a mean number of 69 irradiations (range 53–159). All the patients showed improvement in the range of motion. The PS score was improved from a mean of 40% (pretreatment) to 75% (post-treatment). In western countries, extracorporeal photopheresis (ECP) is the mainstream secondary treatment for sclerodermatous GVHD, and its clinical trial is in progress in Japan. ECP is a promising treatment; however, there are a few problems, such as its high cost and facility accessibility in local areas. Therefore, NB-UVB can be an encouraging alternative to ECP for sclerodermatous GVHD.","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"日本小児血液・がん学会"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"jpn"}]},"item_1617186783814":{"attribute_name":"Identifier","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/20.500.12000/47686"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"2189-5384"},{"subitem_1522646500366":"ISSN","subitem_1522646572813":"2187-011X"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"日本小児血液・がん学会雑誌"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"458","bibliographicPageStart":"453","bibliographicVolumeNumber":"53"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_1522306287251":{"subitem_1522306382014":"DOI","subitem_1522306436033":"https://doi.org/10.11412/jspho.53.453"}},{"subitem_1522306287251":{"subitem_1522306382014":"DOI","subitem_1522306436033":"https://doi.org/10.11412/jspho.53.453"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"53_453.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2011336/files/53_453.pdf"},"version_id":"49732e69-6edb-4482-b4aa-ee27ba5923de"}]},"item_title":"強皮症様皮膚硬化を認める難治性慢性GVHDに対し短波長紫外線照射が奏功した4症例","item_type_id":"15","owner":"1","path":["1642838338003","1642838407795"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-01-29"},"publish_date":"2021-01-29","publish_status":"0","recid":"2011336","relation_version_is_last":true,"title":["強皮症様皮膚硬化を認める難治性慢性GVHDに対し短波長紫外線照射が奏功した4症例"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-08-03T05:33:01.679632+00:00"}