@article{oai:u-ryukyu.repo.nii.ac.jp:02012381,
 author = {Kinjyo, Y. and Kudaka, W. and Toita, T. and Nakamoto, T. and Nagai, Y. and Maemoto, H. and Hashimoto, S. and Ariga, T. and Aoki, Y.},
 issue = {6},
 journal = {European Journal of Gynaecological Oncology},
 month = {Dec},
 note = {Purpose: To review the morbidity and mortality of Stage IVA cervical cancer, with a particular focus on the incidence of fistulae. Materials and Methods: The authors retrospectively analyzed 30 patients with Stage IVA cervical cancer, treated with whole pelvic-external beam radiotherapy (WP-EBRT) and high-dose-rate intracavitary brachytherapy (HDR-ICBT). Results: Seven patients presented with vesicovaginal fistula at the time of cancer diagnosis and six developed a fistula during or after radiotherapy (RT). Fistula was diagnosed 0-41 months after cancer diagnosis. The patients with fistulae had a median survival of 32 months. Six patients are alive, four of whom have no evidence of recurrence, while two have persistent disease. The five-year overall survival (OS) was 14.9% in the patients with fistula and was 39.4% in the total series. On multivariate analysis, RT without HDR-ICBT was an independent prognostic factor. Conclusion: High rates of vesicovaginal fistulae were observed in Stage IVA cervical cancer. Interventions for vesicovaginal fistula to improve quality of life are very important., 論文},
 pages = {938--942},
 title = {Vesicovaginal/rectovaginal fistula formation and outcome of Stage IVA carcinoma of the cervix treated with radiotherapy},
 volume = {38},
 year = {2017}
}