@article{oai:u-ryukyu.repo.nii.ac.jp:02012458,
 author = {Kinjyo, Yoshino and Nagai, Yutaka and Toita, Takafumi and Kudaka, Wataru and Ariga, Takuro and Shimoji, Yuko and Nakasone, Tadaharu and Taira, Yusuke and Arakaki, Yoshihisa and Nakamoto, Tomoko and Wakayama, Akihiko and Ooyama, Takuma and Maemoto, Hitoshi and Heianna, Joichi and Aoki, Yoichi},
 issue = {1076},
 journal = {The British Journal of Radiology},
 month = {},
 note = {Objective:To compare patients with cervical cancer who were primarily treated with concurrent chemoradiotherapy (CCRT) using 20 mg m^<-2> CDDP for 5 days every 3 weeks with weekly regimens of 40 mg m^<-2>. Methods:We retrospectively analyzed 185 patients with Stage IB-IVA squamous-cell carcinoma of the cervix who were treated with CCRT between 2005 and 2013 at our hospital. The CCRT regimen consisted of cisplatin (CDDP) at 20 mg m^<-2> for 5 days every 3 weeks or 40 mg m^<-2> weekly, administered concomitantly with RT. Results:The median age was 50 years (range: 22-70 years) in the triweekly group and was 50.5 years (range: 28-70 years) in the weekly group. The 5-year overall survival rate in the triweekly and weekly groups were 82.0% and 83.3%, respectively (p = 0.851); their disease-free survival rate was 79.6% and 78.1%, respectively (p = 0.672). In the triweekly group, 56 patients (50.9%) had grade 3/4 leukopenia, which was significantly higher than that of 11 patients (15%) in the weekly group (p < 0.0001). Conclusion:The weekly CDDP regimen for CCRT seems better in patients with International Federation of Gynecology and Obstetrics Stages IB-IVA squamous-cell carcinoma of the cervix. Advances in knowledge: The weekly CDDP regimen for CCRT seems better in patients with International Federation of Gynecology and Obstetrics Stages IB-IVA squamous-cell carcinoma of the cervix., 論文},
 title = {Concurrent weekly cisplatin versus triweekly cisplatin with radiotherapy for locally advanced squamous-cell carcinoma of the cervix : a retrospective analysis from a single institution},
 volume = {90},
 year = {2017}
}