{"created":"2022-02-22T03:00:36.190995+00:00","id":2015563,"links":{},"metadata":{"_buckets":{"deposit":"3069177f-d7a2-4b0e-a54d-3838076a6ca0"},"_deposit":{"id":"2015563","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2015563"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02015563","sets":["1642838163960:1642838198944:1642838199408:1642838224252","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"［総説］末梢動脈疾患に対する薬物＋運動療法","subitem_1551255648112":"ja"},{"subitem_1551255647225":"Exercise and Pharmacological Intervention for Patient  with Peripheral Arterial Disease","subitem_1551255648112":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"安, 隆則","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"Yasu, Takanori","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_1522650717957":"ja","subitem_1522651041219":"琉球医学会"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"exercise"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"intermittent"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"claudication"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"heparin"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"peripheral"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"arterial"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"disease"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Trans Atlanticinter-Society Consensus (TASC)) II strongly recommends walking exercise and anti-platelet agents for patients with peripheral arterial disease(PAD).We have reported that a program combining heparin administration with exerciseis a useful therapeutic strategy for stimulation of collateral development in ischemic legs in patients with non-Option PAD via transient increase in hepatocyte growth factor. To examine a hypothesis that additional combination of lipo-Prestaglandin(PG）E1,a Potent vasodilator and inhibitor of platelet aggregation, accelerates the effectiveness of heparin + exercise program in patients with non-option PAD, 20 symptomatic no option PAD (Fontaine II or III）patients were randomly assigned in adouble blind fashion to two groups; a group of lipo-PGEl(+) (supervised walking for 60min/day after intravenous administration of 3,000 units heparin and 10 $ \\mu $g lipo-PGE1 for 14days, n=10) and a group of lipo-PGEl(-) (same supervised walking program after administration of heparin and saline,n=10). After 14-day-initial treatment,the patients of both groups did ambulatory exercise under supervision for 60 min once a day, 3 days/week during a period of following 22 weeks. Additional administration of lipo-PGE1 on heparin + exercise program brings the therapeutic gain appearance forward．This beneficial short-term effect may encourage patients with non-Option PAD to maintain exercise trainlng.","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"琉球医学会"},{"subitem_1522300295150":"en","subitem_1522300316516":"Ryukyu Medical Association"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"jpn"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"1346-888X"},{"subitem_1522646500366":"ISSN","subitem_1522646572813":"0289-1530"},{"subitem_1522646500366":"NCID","subitem_1522646572813":"AN10369445"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"琉球医学会誌 = Ryukyu Medical Journal"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3・4","bibliographicPageEnd":"98","bibliographicPageStart":"95","bibliographicVolumeNumber":"26"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"v26p95.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2015563/files/v26p95.pdf"},"version_id":"17009a5d-9602-49b8-a1e6-4f374897e44c"}]},"item_title":"［総説］末梢動脈疾患に対する薬物＋運動療法","item_type_id":"15","owner":"1","path":["1642838224252","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-02-23"},"publish_date":"2010-02-23","publish_status":"0","recid":"2015563","relation_version_is_last":true,"title":["［総説］末梢動脈疾患に対する薬物＋運動療法"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-10-31T07:40:15.420688+00:00"}