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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球医学会誌
  4. 27巻3・4号
  1. 部局別インデックス
  2. その他

[総説]放射線感受性予測法の確立を目指して : 基礎研究から臨床応用へ

http://hdl.handle.net/20.500.12000/0002015580
http://hdl.handle.net/20.500.12000/0002015580
23aedf33-8282-438a-8d47-87bf24ded0ee
名前 / ファイル ライセンス アクション
v27p81.pdf v27p81.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2010-02-23
タイトル
タイトル [総説]放射線感受性予測法の確立を目指して : 基礎研究から臨床応用へ
言語 ja
タイトル
タイトル Predicting the tumor response to radiotherapy: from basic research to clinical application
言語 en
作成者 小川, 和彦

× 小川, 和彦

ja 小川, 和彦

Search repository
村山, 貞之

× 村山, 貞之

ja 村山, 貞之

Search repository
Ogawa, Kazuhiko

× Ogawa, Kazuhiko

en Ogawa, Kazuhiko

Search repository
Murayama, Sadayuki

× Murayama, Sadayuki

en Murayama, Sadayuki

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 radiotherapy
主題
言語 en
主題Scheme Other
主題 tumor response
主題
言語 en
主題Scheme Other
主題 basic research
主題
言語 en
主題Scheme Other
主題 clinical application
内容記述
内容記述タイプ Other
内容記述 Recently, radiotherapy has become one of the main treatments for cancer patients in Japan. Predicting the tumor response to radiotherapy is one of the major goals of human cancer treatment. In this study, we reviewed the published reports identifying factors that influence radiosensitivity and those indicating the new targets that can enhance the effect of radiotherapy. Factors that may influence radiosensitivity can be divided into intracellular factors and extracellular factors. Intracellular factors include DNA repair, signal transduction, cancer stem cells, growth factors, apoptosis, cell cycle and cell adhesion. Extracellular factors include oxygenation and stroma. Identification of the factors that contribute to radiosensitivity or radioresistance may provide new insights into the mechanisms underlying clinical radioresistance and improve the efficacy of radiotherapy. In future, characterizations of these factors by microarray analysis could help predict responses to radiotherapy in each patient. Moreover, molecular imaging may become a noninvasive and attractive strategy to identify whether it is a radiosensitive or radioresistant tumor before starting radiotherapy.
内容記述
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球医学会
出版者
言語 en
出版者 Ryukyu Medical Association
言語
言語 jpn
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1346-888X
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AN10369445
収録物名
言語 ja
収録物名 琉球医学会誌 = Ryukyu Medical Journal
書誌情報
巻 27, 号 3・4, p. 81-86, 発行日 2008
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