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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球医学会誌
  4. 25巻3・4号
  1. 部局別インデックス
  2. その他

[総説]The Relationship between Physicochemical Properties of Bound Thrombin and Action Mode of Antithrombin Agent on Bound Thrombin

http://hdl.handle.net/20.500.12000/0002015594
http://hdl.handle.net/20.500.12000/0002015594
6a63e9e2-5484-4a8a-b232-f3d69d23cf4b
名前 / ファイル ライセンス アクション
v25p85.pdf v25p85.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2010-02-23
タイトル
タイトル [総説]The Relationship between Physicochemical Properties of Bound Thrombin and Action Mode of Antithrombin Agent on Bound Thrombin
言語 ja
作成者 Nakamura, Mariko

× Nakamura, Mariko

en Nakamura, Mariko

Sunagawa, Masanori

× Sunagawa, Masanori

en Sunagawa, Masanori

Yoshioka, Miwa

× Yoshioka, Miwa

en Yoshioka, Miwa

Tengan, Hiroatsu

× Tengan, Hiroatsu

en Tengan, Hiroatsu

Takara, Shigeru

× Takara, Shigeru

en Takara, Shigeru

Nakamura, Kazunao

× Nakamura, Kazunao

en Nakamura, Kazunao

Kimura, Yasutaka

× Kimura, Yasutaka

en Kimura, Yasutaka

Motomura, Makoto

× Motomura, Makoto

en Motomura, Makoto

Tamaki, Minao

× Tamaki, Minao

en Tamaki, Minao

Uehara, Ken

× Uehara, Ken

en Uehara, Ken

Kinjoh, Kiyohiko

× Kinjoh, Kiyohiko

en Kinjoh, Kiyohiko

Kosugi, Tadayoshi

× Kosugi, Tadayoshi

en Kosugi, Tadayoshi

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 bound thrombin
言語 en
主題Scheme Other
主題 thrombolytic therapy
言語 en
主題Scheme Other
主題 coronary intervention
言語 en
主題Scheme Other
主題 anticoagulant agents
言語 en
主題Scheme Other
主題 structure and function relationship
内容記述
内容記述タイプ Other
内容記述 Procoagulant activity was known to increase after thrombolytic therapy. It was thought that the enhancement of procoagulant activity was dependent upon the new generation and development of novel kinds of thrombin after thrombolytic therapy. Such thrombin was also produced by percutaneous transluminal coronary angioplasty (PTCA) and percutaneous transluminal coronary reperfusion (PTCR) , resulting in unexpected rethrombosis and vascular restenosis. That is, thrombin appeared again in the circulating blood after thrombolysis or mechanical destruction of the previously formed thrombus. Such the newly generated thrombin was termed postclotting thrombin (bound thrombin). The postclotting thrombins were divided into three classes: native, intact, and bound thrombin. It was emphasized in this review that the bound thrombin generated during the formation of fibrin or thrombus has the clotting activity like a native thrombm. The reliable control of the bound thrombin using synthetic antithrombin agents led the clinical doctors to reasonable haemostasis, tissue repair and regeneration, and prevention from atherosclerotic change of blood vessel
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球医学会
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1346-888X
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子タイプ NCID
収録物識別子 AN10369445
収録物名
言語 ja
収録物名 琉球医学会誌 = Ryukyu Medical Journal
書誌情報
巻 25, 号 3・4, p. 85-93
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