{"created":"2022-02-22T03:01:45.371726+00:00","id":2015603,"links":{},"metadata":{"_buckets":{"deposit":"0dd7f47d-ab7a-458f-bd8c-d0f1ca271d20"},"_deposit":{"id":"2015603","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2015603"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02015603","sets":["1642838163960:1642838198944:1642838199408:1642838222821","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"［原著］A Prospective Trial of Oral Betamethason and Oral Lorazepam in the Management of Delayed Nausea and Vomiting Induced by Cisplatin-Based Chemotherapy","subitem_title_language":"ja"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Uehara, Tadashi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yohena, Tomofumi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kanematsu, Takanori","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Teruya, Takao","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ikeda, Jiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Okamoto, Junichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Asoh, Hiroshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ichinose, Yukito","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"琉球医学会","subitem_rights_language":"ja"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Betamethason","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Chemotherapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cisplatm","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Delayed emesis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Lorazepam","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Lung Cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Purpose: The optimal treatment modality for delayed emesis occurring later than 24 hours after the administration of cisplatin-based chemotherapy has not yet been established. Patients and Methods: Twenty patients received 5-hydroxytryptamine 3 receptor antagonist intravenously for the treatment of acute emesis just before cisplatm infusion in the first cycle of treatment, and the thereafter they received oral administration of betamethason ($\\2mgtimes3/day$) plus oral lorazepam ($\\0.5mgtimes3/day$) for 5 days in trial I. In trial II, 14 patients who received the other anti-emetic regimen (methylprednisolone plus metoclopramide) for delayed emesis in the first cycle of chemotherapy were treated by this regimen for the second cycle of treatment. A complete response (CR) was defined as no emetic episodes and a partial response (PR) as no vomiting episodes but some nausea. The effects of anti-emetic treatments were evaluated for 5 days from the next day after cisplatin administration. Results: The mean control rate (percentage of CR+PR) and CR rate for delayed emesis for the 5-day period were 97% and 84%, respectively in trial I. The mean control rate in patients undergoing the other anti-emetic regimen in the first cycle of chemotherapy was 60% compared to 96% in the same patients undergoing this regimen in the second cycle of the same chemotherapy in trial II. Conclusions: Oral betamethason plus lorazepam demonstrated a high control rate for delayed nausea and vomiting induced by cisplatin-based chemotherapy.","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"琉球医学会","subitem_publisher_language":"ja"},{"subitem_publisher":"Ryukyu Medical Association","subitem_publisher_language":"en"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"1346-888X","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"0289-1530","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AN10369445","subitem_source_identifier_type":"NCID"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_source_title":"琉球医学会誌 = Ryukyu Medical Journal","subitem_source_title_language":"ja"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1・2","bibliographicPageEnd":"22","bibliographicPageStart":"17","bibliographicVolumeNumber":"25"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"v25p17.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2015603/files/v25p17.pdf"},"version_id":"0536789a-c3f3-498c-add7-9174f8f4278e"}]},"item_title":"［原著］A Prospective Trial of Oral Betamethason and Oral Lorazepam in the Management of Delayed Nausea and Vomiting Induced by Cisplatin-Based Chemotherapy","item_type_id":"15","owner":"1","path":["1642838222821","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-02-23"},"publish_date":"2010-02-23","publish_status":"0","recid":"2015603","relation_version_is_last":true,"title":["［原著］A Prospective Trial of Oral Betamethason and Oral Lorazepam in the Management of Delayed Nausea and Vomiting Induced by Cisplatin-Based Chemotherapy"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-10-31T07:40:58.133314+00:00"}