{"created":"2022-02-22T03:13:46.887879+00:00","id":2015727,"links":{},"metadata":{"_buckets":{"deposit":"03c774ea-3e1b-4575-8c7b-7c50b40e1f52"},"_deposit":{"id":"2015727","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2015727"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02015727","sets":["1642838163960:1642838198944:1642838233003:1642838238794","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"[原著］Effects of Some Anti-Anginal Drugson Ergonovine-Induced Contractions of Isolated Dog Coronary Arteries","subitem_1551255648112":"ja"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sakanashi, Matao","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ito, Hirosumi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Noguchi, Katsuhiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nagamine, Fumio","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_1522650717957":"ja","subitem_1522651041219":"琉球医学会"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"Dog coronary artery"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"Ergonovine"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"Contraction"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"Alpha adrenoceptor"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"Anti-anginal drug"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Effects of some anti-anginal drugs on dog coronary arterial contractions induced by ergonovine were investigated in vitro under potassium-contracture. Administrations of phentolamine (10^<-6>g/ml) or phenoxybenzamine (3x1O^<-6>g/ml) did not affect potassium-contracture and ergonovine (10^<-6>g/ml)-induced contractions of coronary arterial strips, but phentolamine at a higher dose (10^<-5>g/ml) depressed both of them. Dihydroergotamine (10^<-7> -10^<-6>g/ml) produced further contractions of the strips under potassium-contracture and dose-dependently depressed ergonovine-induced contractions. Contractile responses to ergonovine (10^<-6>g/ml) were depressed by prior administrations of nitroglycerin (10^<-7>-10^<-6>g/ml), nifedipine (10^<-8>-10^<-7>g/ml), diltiazem(10^<-6>-10^<-5>g/ml) and SG-75 (10^<-6>-10^<-5>g/ml)in a dose-dependent fashion. Results indicate that ergonovine-induced contractions of isolated dog coronary arteries under potassium-contracture are not mediated mainly through an activation of alpha adrenoceptors and that some anti-anginal drugs such as nitroglycerin, nifedipine, diltiazem and SG-75 have a depressant action on these contractions.","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"琉球大学医学部"},{"subitem_1522300295150":"en","subitem_1522300316516":"Faculty of Medicine, University of the Ryukyus"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"0289-1530"},{"subitem_1522646500366":"NCID","subitem_1522646572813":"AN10027430"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"琉球大学医学会雑誌 : 医学部紀要 = Ryukyu medical journal"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1986","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"88","bibliographicPageStart":"81","bibliographicVolumeNumber":"9"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"v9p81.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2015727/files/v9p81.pdf"},"version_id":"eeda58dd-e215-4e6b-b641-357ad445725d"}]},"item_title":"[原著］Effects of Some Anti-Anginal Drugson Ergonovine-Induced Contractions of Isolated Dog Coronary Arteries","item_type_id":"15","owner":"1","path":["1642838238794","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-06-30"},"publish_date":"2010-06-30","publish_status":"0","recid":"2015727","relation_version_is_last":true,"title":["[原著］Effects of Some Anti-Anginal Drugson Ergonovine-Induced Contractions of Isolated Dog Coronary Arteries"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-10-31T07:43:22.809490+00:00"}