@article{oai:u-ryukyu.repo.nii.ac.jp:02015850,
 author = {Faisal, Muazzam A and Yoshihiro, Muto},
 issue = {4},
 journal = {琉球医学会誌 = Ryukyu Medical Journal},
 month = {},
 note = {To evaluate the specificity and efficacy of lectin histochemical staining characteristics on human colorectal neoplastic and adjacent non-neoplastic tissue, a thorough comparative study has been performed to that of a recognized colorectal tumor marker,carcinoembryonic antigen (CEA). Neoplastic tissue and adjacent non-neoplastic mucosa of 26 surgically extirpated specimens were examined lectin histochemically by four differentlectins (Ulex europaeus-I. Arachis hypogaea, Triticum vulgare and Canavaha ensiformis) and immunohistochemically by anti CEA antibody. According to their degree of staining all the four lectins(UEA-I moderate 57.69%, extensive 39.42%; PNA moderate 60.57% extensive 5.76%; WGA moderate 76.92% extensive 1.92% and Con-A moderate 48.07%. extensive 51.29%) and CEA (moderate 66.34%,extensive 22.11%)showed very high percentages of positive staining for neoplastic tissues but almost reciprocal results were observed by UEA-I (moderate 7.69%, extensive O%) and partially by PNA lectin (moderate 15.38%,extensive O%) for non-neoplastic mucosa (P<0.01). While CEA (moderate 50%, extensive 19.23%) and the other two lectins did not show much differences in their staining percentages for non-neoplastic mucosa (P>0.05). Further study regarding their staining pattern revealed that for neoplastic tissues UEA-I mainly stained the cytoplasmic (without polarity) (60.58%) or the stromal (28.85%) types but in case of non-neoplastic mucosa the cytoplasmic (with polarity) (57.15%) or the apical (35.71%) types predominated. No such distinct staining patterens were observed for CEA and the other lectins. From our study it is strongly suggestive that UEA-I lectinis by far morespecific and localized for the malignant transformation of colorectal tissues with compared to that of carcinoembryonic antigen, CEA., 論文},
 pages = {295--306},
 title = {[原著］A Histochemical Comparative Study on Four Different Types of Lectins and Carcinoembryonic Antigen (CEA) on Human Colorectal Tissues},
 volume = {12},
 year = {1992}
}