{"created":"2022-02-22T03:30:12.371456+00:00","id":2015850,"links":{},"metadata":{"_buckets":{"deposit":"49d32c2a-e6cb-466f-86dd-963e82a53c7f"},"_deposit":{"id":"2015850","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2015850"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02015850","sets":["1642838163960:1642838198944:1642838199408:1642838201426","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"[原著］A Histochemical Comparative Study on Four Different Types of Lectins and Carcinoembryonic Antigen (CEA) on Human Colorectal Tissues","subitem_1551255648112":"ja"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Faisal, Muazzam A","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yoshihiro, Muto","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_1522650717957":"ja","subitem_1522651041219":"琉球医学会"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"colon and rectum"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"neoplastic lesion"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"adjacent non-neoplastic mucosa"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"UEA-1 and CEA."}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"To evaluate the specificity and efficacy of lectin histochemical staining characteristics on human colorectal neoplastic and adjacent non-neoplastic tissue, a thorough comparative study has been performed to that of a recognized colorectal tumor marker,carcinoembryonic antigen (CEA). Neoplastic tissue and adjacent non-neoplastic mucosa of 26 surgically extirpated specimens were examined lectin histochemically by four differentlectins (Ulex europaeus-I. Arachis hypogaea, Triticum vulgare and Canavaha ensiformis) and immunohistochemically by anti CEA antibody. According to their degree of staining all the four lectins(UEA-I moderate 57.69%, extensive 39.42%; PNA moderate 60.57% extensive 5.76%; WGA moderate 76.92% extensive 1.92% and Con-A moderate 48.07%. extensive 51.29%) and CEA (moderate 66.34%,extensive 22.11%)showed very high percentages of positive staining for neoplastic tissues but almost reciprocal results were observed by UEA-I (moderate 7.69%, extensive O%) and partially by PNA lectin (moderate 15.38%,extensive O%) for non-neoplastic mucosa (P<0.01). While CEA (moderate 50%, extensive 19.23%) and the other two lectins did not show much differences in their staining percentages for non-neoplastic mucosa (P>0.05). Further study regarding their staining pattern revealed that for neoplastic tissues UEA-I mainly stained the cytoplasmic (without polarity) (60.58%) or the stromal (28.85%) types but in case of non-neoplastic mucosa the cytoplasmic (with polarity) (57.15%) or the apical (35.71%) types predominated. No such distinct staining patterens were observed for CEA and the other lectins. From our study it is strongly suggestive that UEA-I lectinis by far morespecific and localized for the malignant transformation of colorectal tissues with compared to that of carcinoembryonic antigen, CEA.","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"琉球医学会"},{"subitem_1522300295150":"en","subitem_1522300316516":"Ryukyu Medical Association"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"1346888X"},{"subitem_1522646500366":"ISSN","subitem_1522646572813":"0289-1530"},{"subitem_1522646500366":"NCID","subitem_1522646572813":"AN10369445"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"琉球医学会誌 = Ryukyu Medical Journal"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"306","bibliographicPageStart":"295","bibliographicVolumeNumber":"12"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"v12p295.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2015850/files/v12p295.pdf"},"version_id":"7ece71d9-a7a5-40c2-94b4-445e2c96af28"}]},"item_title":"[原著］A Histochemical Comparative Study on Four Different Types of Lectins and Carcinoembryonic Antigen (CEA) on Human Colorectal Tissues","item_type_id":"15","owner":"1","path":["1642838201426","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-07-02"},"publish_date":"2010-07-02","publish_status":"0","recid":"2015850","relation_version_is_last":true,"title":["[原著］A Histochemical Comparative Study on Four Different Types of Lectins and Carcinoembryonic Antigen (CEA) on Human Colorectal Tissues"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-10-31T07:45:40.557352+00:00"}