{"created":"2022-02-22T03:30:40.408645+00:00","id":2015866,"links":{},"metadata":{"_buckets":{"deposit":"859ae9fb-415a-4261-abdb-c1bb13320ada"},"_deposit":{"id":"2015866","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2015866"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02015866","sets":["1642838163960:1642838198944:1642838199408:1642838201426","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"[\u539f\u8457\uff3d\u62e1\u5927\u809d\u5207\u9664\u6642\u306b\u7db2\u5185\u7cfb\u8ce6\u62ec\u5264\u306e\u6295\u4e0e\u3084\u813e\u6458\u306e\u610f\u7fa9\u306b\u95a2\u3059\u308b\u5b9f\u9a13\u7684\u7814\u7a76","subitem_1551255648112":"ja"},{"subitem_1551255647225":"Experimental study of implication of activation of reticuloendothelial function by injection of OK-432 and splenectomy on 93% hepatectomy in rats","subitem_1551255648112":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"\u5bae\u826f, \u7403\u4e00\u90ce","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"Miyara, Kyuichirou","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_1522650717957":"ja","subitem_1522651041219":"\u7409\u7403\u533b\u5b66\u4f1a"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"93%hepatectomy"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"OK-432"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"splenectomy"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"reticuloendotherial function"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"The purpose of this study is to evaluate the influence of increased activity of reticuloendothelial function by OK-432 and splenectomy on hepatic regeneration following 93% hepatectomy in rats. Wister-maie rats weighting 240g to 320g were randomly allocated to 4 experimental groups and subjected to the following regimen :(1) A group; 93% hepatectomy alone,(2) B group; 93% hepatectomy+splenectomy, (3) C group; OK-432+93% hepatectomy, (4) D group; OK-432+93% hepatectomy+splenectomy. Survival rates after hepatectomy, initial, 24hour, 48hour, serum endotoxin, S- GOT, S-GPT in each group were determined. The long-term (180 days following hepatectomy) survival rates was 45.5% in A group, 13.6% in B group, 6.4% in Cgroup and 6.3% in D group, respectively and A group survival was statistically significant better compared with other three groups. Serum endotoxin titers prior to hepatectomy were significantly lower (0.926 pg/ml) in OK-432 treated groups than in non-treated groups (3.3pg/ml). 24hours after hepatectomy, A group showed marked increase titers of endotoxin with statistical significance compared with other three groups. S-GOT and S-GPT markedly elevated 24hours after hepatectomy, but returned to the normal values 48hours after hepatectomy. These results might suggest that in 93% experimental hepatectomy in rats, activation of reticuloendotherial function could be harmful in liver regeneration after hepatectomy, and lower survival rate from the long-term survival points, therefore, another unknown mechanism might play an important role in liver damage after hepatectomy.","subitem_description_type":"Other"},{"subitem_description":"\u8ad6\u6587","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"\u7409\u7403\u533b\u5b66\u4f1a"},{"subitem_1522300295150":"en","subitem_1522300316516":"Ryukyu Medical Association"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"jpn"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"1346888X"},{"subitem_1522646500366":"ISSN","subitem_1522646572813":"0289-1530"},{"subitem_1522646500366":"NCID","subitem_1522646572813":"AN10369445"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"\u7409\u7403\u533b\u5b66\u4f1a\u8a8c = Ryukyu Medical Journal"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"326","bibliographicPageStart":"317","bibliographicVolumeNumber":"12"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"v12p317.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2015866/files/v12p317.pdf"},"version_id":"969aa1bd-aee2-4560-91a9-f343e4e345dd"}]},"item_title":"[\u539f\u8457\uff3d\u62e1\u5927\u809d\u5207\u9664\u6642\u306b\u7db2\u5185\u7cfb\u8ce6\u62ec\u5264\u306e\u6295\u4e0e\u3084\u813e\u6458\u306e\u610f\u7fa9\u306b\u95a2\u3059\u308b\u5b9f\u9a13\u7684\u7814\u7a76","item_type_id":"15","owner":"1","path":["1642838201426","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-07-02"},"publish_date":"2010-07-02","publish_status":"0","recid":"2015866","relation_version_is_last":true,"title":["[\u539f\u8457\uff3d\u62e1\u5927\u809d\u5207\u9664\u6642\u306b\u7db2\u5185\u7cfb\u8ce6\u62ec\u5264\u306e\u6295\u4e0e\u3084\u813e\u6458\u306e\u610f\u7fa9\u306b\u95a2\u3059\u308b\u5b9f\u9a13\u7684\u7814\u7a76"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-10-31T07:45:58.852901+00:00"}