{"created":"2022-02-22T03:31:25.497143+00:00","id":2015892,"links":{},"metadata":{"_buckets":{"deposit":"a81c3003-ba6d-455b-aa79-395e153d86f1"},"_deposit":{"id":"2015892","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2015892"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02015892","sets":["1642838163960:1642838198944:1642838199408:1642838200917","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"[原著］Specific and Sensitive Estradiol-17 $ \\beta $ Radioimmunoassay","subitem_1551255648112":"ja"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kono, Shinzo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Sunagawa, Hajime","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_1522650717957":"ja","subitem_1522651041219":"琉球医学会"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"radioimmunoassay"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"estradiol-17 $ \\beta $"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"postmenopausal women"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"A specific and highly sensitive radioimmunoassay of estradiol-17$ \\beta $ (E_2-17$ \\beta $) was developed. Ether was used to extract E_2-I7 from 0.5ml plasma samples and the extract was then purified by Sephadex LH-20 column chromatography and measured using an anti-serum to E_2-6-BSA and I^<125>-labelled E_2-17$ \\beta $ Sensitivity of the method was 2.5pg/ml. The coefficient of variation in accuracy and precision of the method was under 15%. The unconjugated E_2-17$ \\beta $ concentration in sera of 21 postmenopausal women ranged from 2.5 to 14.1 pg/ml. In serum samples over 10 pg/ml investigated by the direct method, E_2-17$ \\beta $ values determined by the present method correlated well with the direct method (r=0.91,pく0.001, N=87). In samples under 10 pg/ml determined by the direct method, E_2-17$ \\beta $ value ranged from 2.5 to 23.5 pg/ml by the present method. The present method might be useful for more accurate evaluations of ovarian functions.","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"琉球医学会"},{"subitem_1522300295150":"en","subitem_1522300316516":"Ryukyu Medical Association"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"1346888X"},{"subitem_1522646500366":"ISSN","subitem_1522646572813":"0289-1530"},{"subitem_1522646500366":"NCID","subitem_1522646572813":"AN10369445"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"琉球医学会誌 = Ryukyu Medical Journal"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"225","bibliographicPageStart":"219","bibliographicVolumeNumber":"12"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"v12p219.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2015892/files/v12p219.pdf"},"version_id":"e2eab14a-5253-4424-9769-351c9fb7a8cc"}]},"item_title":"[原著］Specific and Sensitive Estradiol-17 $ \\beta $ Radioimmunoassay","item_type_id":"15","owner":"1","path":["1642838200917","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-07-02"},"publish_date":"2010-07-02","publish_status":"0","recid":"2015892","relation_version_is_last":true,"title":["[原著］Specific and Sensitive Estradiol-17 $ \\beta $ Radioimmunoassay"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-10-31T07:46:28.311761+00:00"}