@article{oai:u-ryukyu.repo.nii.ac.jp:02015919,
 author = {島袋, 泰 and 平良, 豊 and 湯佐, 祚子 and 戸沢, 好美 and 奥島, しょう子 and 富村, 賢志 and 折田, 均 and 上原, 憲全 and 徳嶺, 譲芳 and 太田, 敏久 and 伊波, 寛 and 奥田, 佳朗},
 issue = {4},
 journal = {琉球医学会誌 = Ryukyu Medical Journal},
 month = {},
 note = {Effects of prostaglandin E_1(PGE_1) induced hypotensive anesthesia on intraoperative blood loss, blood transfusion volume, and renal and liver function were studied on 26 patients (34-75 years old) during orthopedic lower extremities procedures. The hypotension was induced by continuous drip infusion of PGE_1 untill systolic blood pressure drops to 90-100 mmHg under ethrane/N_2O anesthesia. During knee joint replacement procedure, blood loss and blood transfusion were significantly reduced in PGE_1 induced hypotensive patients (PGE_1 group; n= 6) compared with normotensive patients (control group; n=6). No significant change in postoperative deta indicating renal function was noted in PGE_1 group (n=12) compared with preoprative deta and that of control group (n=14). Also postoperative deta indicating liver function were within normal limit in PGE_1 group, except LDH. These results suggest that PGE_1 can be used safely in older patients to control blood pressure in order to reduce intraoperative blood loss and blood transfusion., 論文},
 pages = {361--366},
 title = {[原著］下肢手術症例に対するPGE_1使用 : 低血圧麻酔の検討},
 volume = {12},
 year = {1992}
}