@article{oai:u-ryukyu.repo.nii.ac.jp:02015946, author = {Sakugawa, Hiroshi and Nakasone, Hiroki and Kawakami, Yuko and Nakayoshi, Tomofumi and Kinjo, Fukunori and Saito, Atsushi and Ikema, Minoru and Yamashiro, Akihiro and Nakayoshi, Tomokuni}, issue = {3}, journal = {琉球医学会誌 = Ryukyu Medical Journal}, month = {}, note = {To compare the clinical utility of type IV collagen 7S domain and hyaluronate, as markers in the evaluation of liver fibrosis, 184 patients with biopsy-proven chronic viral liver disease (32; type B, 152; type C) were involved in this study. The two markers correlated well with the grade of liver fibrosis. The correlation coefficients of 7S-collagen and hyaluronate with the extent of fibrosis were 0.747 and 0.813, respectively. Very high values were seen more frequently in hyaluronate than in 7S-collagen, particularly in patients with moderate and severe fibrosis. Both markers also correlated strongly with conventional liver function tests except for alanine aminotransferase. In conclusion, serum hyaluronate was a more sensitive marker and seemed to more strongly correlate with the degree of hepatic fibrosis than type IV collagen 7S domain., 論文}, pages = {133--137}, title = {[原著]Comparison of clinical utility between type IV collagen 7S domain and hyaluronate in patients with chronic viral liver disease}, volume = {15}, year = {1995} }