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[原著]The effects of compression of the bundle of nerves and vessels at the internal auditory meatus on cochlear blood flow and acoustically evoked responses
http://hdl.handle.net/20.500.12000/0002015947
http://hdl.handle.net/20.500.12000/0002015947765ede7e-498b-492e-823d-893ef12d1687
名前 / ファイル | ライセンス | アクション |
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Item type | デフォルトアイテムタイプ(フル)(1) | |||||||||
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公開日 | 2010-07-02 | |||||||||
タイトル | ||||||||||
タイトル | [原著]The effects of compression of the bundle of nerves and vessels at the internal auditory meatus on cochlear blood flow and acoustically evoked responses | |||||||||
言語 | ja | |||||||||
作成者 |
Tang, Anzhou
× Tang, Anzhou
× Ura, Masaharu
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アクセス権 | ||||||||||
アクセス権 | open access | |||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
権利情報 | ||||||||||
言語 | ja | |||||||||
権利情報 | 琉球医学会 | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | internal auditory artery | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | cochlear nerve | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | cochlear blood flow | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | acoustically evoked responses | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | acoustic neuroma | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | This study was performed to observe the changes in cochlear blood flow (CoBF), the compound action potentials (CAP) and auditory brainstem response (ABR) in the pressure-induced animal model of acoustic neuroma. By suboccipital approach, the bundle of nerves and vessels (BNV) at the entrance of the internal auditory meatus in the guinea pig was exposed, and two pressure points, one being anterior to and the other being posterior to the center of the bundle were selected to compress. After compression, the changes in CoBF, CAP and ABR were determined in a total of 31 animals. According to the responses of CoBF, we classified these changes into three types as follows: complete decrease (type I), incomplete decrease (type II) and increase in CoBF (type III). The proportion of change in each type revealed significant differences between the two pressure points. Seventy-four percent (14/19) of the compressions at the posterior point showed type I, whereas 67% (8/12) of the compressions at the anterior point showed type III. CAP and ABR in each type were closely related to CoBF. In type I and II, CAP and ABR deteriorated, and the deteriorations of both were attributed to cochlear ischemia. After transient occlusion of CoBF, N_1 of CAP was able to recover. The degrees of N_1 recovery were dependent not only on the ischemic duration but also on the degree of decrease in CoBF during ischemia. On the other hand, although there was no decrease in CoBF and wave I in type III, I-II interwave latency delay with decrease in the amplitudes of wave II-IV was observed. It is suggested that the changes in type III were mainly caused by the blockage of the cochlear nerve. The results presented in this study indicate that compression will induce damages to both the internal auditory artery and the cochlear nerve, depending mainly on the compression position. The mechanisms responsible for hearing loss caused by acoustic neuroma were discussed based on this pressure-induced model. | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | 論文 | |||||||||
出版者 | ||||||||||
言語 | ja | |||||||||
出版者 | 琉球医学会 | |||||||||
出版者 | ||||||||||
言語 | en | |||||||||
出版者 | Ryukyu Medical Association | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
資源タイプ | ||||||||||
資源タイプ | journal article | |||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
出版タイプ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
収録物識別子 | ||||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 1346888X | |||||||||
収録物識別子 | ||||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 0289-1530 | |||||||||
収録物識別子 | ||||||||||
収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AN10369445 | |||||||||
収録物名 | ||||||||||
言語 | ja | |||||||||
収録物名 | 琉球医学会誌 = Ryukyu Medical Journal | |||||||||
書誌情報 |
巻 15, 号 4, p. 181-188, 発行日 1995 |