@article{oai:u-ryukyu.repo.nii.ac.jp:02015954, author = {高宮城, 敦 and 上原, 啓志 and 長嶺, 安司 and 稲福, 和宏 and 野中, 薫雄 and Takamiyagi, Atsushi and Uehara, Keishi and Nagamine, Yasushi and Inafuku, Kazuhiro and Nonaka, Shigeo}, issue = {1}, journal = {琉球医学会誌 = Ryukyu Medical Journal}, month = {}, note = {Okinawa is an area in Japan where ultraviolet radiation (UVR) is particularly strong due to its southern location. Recently, an increase in UVR reaching the earth's surface due to ozone depletion has become a major concern. It is important to know the existing state and prevalence of skin tumors related to UVR, but to our knowledge no studies have been reported in Okinawa. Solar keratosis (SK) and squamous cell carcinoma (SCC) are induced by UVR. We studied statistically and pathologically, records of SK and SCC in Okinawa. The total number of cases studied at the University of Ryukyus Hospital was 251, comprising 119 SK and 132 SCC. The male-female ratio was 1:2.1 and 1:1.1 for SK and SCC respectively. Theaverage age was 74.7 years (male: 71.7, female: 76.0) for SK and 72.8 years (male: 68.6, female: 76.8) for SCC. Facial SCC was 40.2% (male: 26.6%, female: 52.9%). The total number of facial SK and SCC from 1989 to 1994 was higher compared with 1983 to 1988. The increase is not due to UVR, because data from the Okinawa Meteorological Observatory shows no remarkable change in the intensty of UVR. Histopathological evaluation showed that 28.8% of all SCC originated from SKs, this number being higher than that of other areas in Japan. Interestingly, both SK and SCC occurred frequently on the face of elderly women, indicating that women in Okinawa are exposed to the sun more than their male counterparts. We conclude that UVR in combination with other factors may be the etiologic agents influencing the development of both SK and SCC., 論文}, pages = {27--31}, title = {[原著]沖縄県における光線角化症と有棘細胞癌の統計的視察}, volume = {16}, year = {1996} }