{"created":"2022-02-22T04:09:58.292587+00:00","id":2015977,"links":{},"metadata":{"_buckets":{"deposit":"d88a508f-d0af-4983-984c-024263dfc168"},"_deposit":{"id":"2015977","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2015977"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02015977","sets":["1642838163960:1642838198944:1642838199408:1642838205767","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"[総説］Nucleic acids and their components : A requirement for cellular development and immune function","subitem_1551255648112":"ja"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yamamoto,Shigeru","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Adjei, AndrewA.","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_1522650717957":"ja","subitem_1522651041219":"琉球医学会"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"nucleoside"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"nucleotide"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"infection"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"immunity"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"parenteral formula"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"enteral formula"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Dietary sources of nucleic acids and their components (nucleosides and nucleotides) have not been considered to be essential for normal growth and development. The liver has an active de novo synthesis of nucleic acid components and supplies them to some tissues such as intestinal epithelium and lymphoid cells which lack the de novo synthesis. However in certain clinical conditions such as infection and surgical stress the requirement of the components increases and the endogenous supply becomes insufficent. In such circumstances, the cells require exogenous sources. The significance of exogenously administered nucleic acids and their components for opitimal function of cellular development and immune response is reviewed.","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"琉球医学会"},{"subitem_1522300295150":"en","subitem_1522300316516":"Ryukyu Medical Association"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"1346888X"},{"subitem_1522646500366":"ISSN","subitem_1522646572813":"0289-1530"},{"subitem_1522646500366":"NCID","subitem_1522646572813":"AN10369445"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"琉球医学会誌 = Ryukyu Medical Journal"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1995","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"17","bibliographicPageStart":"13","bibliographicVolumeNumber":"15"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"v15_1p13.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2015977/files/v15_1p13.pdf"},"version_id":"8d161625-9721-43b3-8f67-993e6efd77e5"}]},"item_title":"[総説］Nucleic acids and their components : A requirement for cellular development and immune function","item_type_id":"15","owner":"1","path":["1642838205767","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-07-02"},"publish_date":"2010-07-02","publish_status":"0","recid":"2015977","relation_version_is_last":true,"title":["[総説］Nucleic acids and their components : A requirement for cellular development and immune function"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-10-31T07:48:00.273357+00:00"}