@article{oai:u-ryukyu.repo.nii.ac.jp:02016001,
 author = {豊田, 善成 and 仲宗根, 克 and 大城, 朝光 and 喜友名, 正也 and Sadi, AlMuktafi and Hye, MdAbdul and 鏡平名, 光三 and 戸田, 隆義 and 山根, 誠久 and 砂川, 涼子 and Toyoda, Zensei and Nakasone, Katsu and Oshiro, Choko and Kiyuna, Masaya and Sadi, AlMuktafi and Hye, MdAbdul and Yohena, Kozou and Toda, Takayoshi and Yamane, Nobuhisa and Sunagawa, Ryoko},
 issue = {3},
 journal = {琉球医学会誌 = Ryukyu Medical Journal},
 month = {},
 note = {Cytological examinations of the ascitic fluid taken from the patient of malignant melanoma were reported. A 52-year-old woman had a skin tumor in her right sole. The tumor was diagnosed as malignant melanoma by biopsy at a private hospital in March 1988. In October 1988, the patient transferred to the Department of Dermatology, University of the Ryukyus Hospital, where she was undergone radical excision of right sole followed by chemotherapy (Dacarvazin, Adriamycin and vincristin) and interferon therapy. Histo10gical diagnosis of the tumor was a malignant melanoma acral lentiginous type. In February 1995, ascitic effusion was noted, and yellowish fluid was collected by tapping. Round shaped tumor cells containing irregular nuclei with prominent nucleoli were observed by Papanicolaou-stain and suggested the recurrence of malignant melanoma. The cytoplasm of the cells contained abundant fine granular melanin pigments. Intranuclear vacuolations were also observed in several tumor cells. Immunocytochemically the tumor celIs were positive for both S- 100 protein and neuron-specific-enolase (NSE) staining. Electron microscopic examination showed l irregular shaped nuclei with prominent nucleoli and melanosomes in the cytoplasm. We suggest that immunocytochemical staining and electron microscopic examination of the ascitic fluid may beuseful for diagnosis of malignant melanoma cytology., 論文},
 pages = {143--146},
 title = {[症例報告]腹水中に出現した皮膚原発悪性黒色腫一症例の細胞学的検討 : 特に細胞像を中心に},
 volume = {16},
 year = {1996}
}