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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球医学会誌
  4. 15巻2号
  1. 部局別インデックス
  2. その他

[原著]Administration of histamine-rat gammaglobulin conjugate suppresses IgE production in rats

http://hdl.handle.net/20.500.12000/0002016013
http://hdl.handle.net/20.500.12000/0002016013
c61da6d0-b422-4c76-b163-d98552439b31
名前 / ファイル ライセンス アクション
v15p13.pdf v15p13.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2010-07-02
タイトル
タイトル [原著]Administration of histamine-rat gammaglobulin conjugate suppresses IgE production in rats
言語 ja
作成者 Hanashiro, Kazuhiko

× Hanashiro, Kazuhiko

en Hanashiro, Kazuhiko

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Sunagawa, Masanori

× Sunagawa, Masanori

en Sunagawa, Masanori

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Saitoh, Shigeru

× Saitoh, Shigeru

en Saitoh, Shigeru

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Nakamura, Mariko

× Nakamura, Mariko

en Nakamura, Mariko

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Kosugi, Tadayoshi

× Kosugi, Tadayoshi

en Kosugi, Tadayoshi

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 histamine-rat gammaglobulin conjugate (HRG)
主題
言語 en
主題Scheme Other
主題 IgE
主題
言語 en
主題Scheme Other
主題 suppression
内容記述
内容記述タイプ Other
内容記述 We evaluated the effect of administration of histamine-rat gammaglobulin conjugate (HRG) on the production of IgE in rats. The antigen-specific IgE level in the serum measured by PCA reaction decreased in the HRG-administered group, compared to that in the physiological saline-administered control group on day 15 after sensitization with DNP-Ascaris antigen. However, on day 10, HRG significantly increased the concentration of histamine compared to that in the control group. The IgG_1 level was higher in the HRG-administered group on day 15 and day 20, compared to that in the control group. From these results and the observation that the IgE production in rats increased to the highest level on day 15, we concluded that the decrease in PCA titer induced by the administration of HRG in rats was not dependent on an increase in IgE consumption, but on a decrease in IgE production. The increased histamine and IgG_1 level by the administration of HRG might have directly or indirectly suppressed the IgE production in rats.
内容記述
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球医学会
出版者
言語 en
出版者 Ryukyu Medical Association
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1346888X
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AN10369445
収録物名
言語 ja
収録物名 琉球医学会誌 = Ryukyu Medical Journal
書誌情報
巻 15, 号 2, p. 13-17, 発行日 1995
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