@article{oai:u-ryukyu.repo.nii.ac.jp:02016014,
 author = {伊藤, 悦男 and 嘉陽, 清美 and 新垣, 有正 and 森岡, 孝満 and 宮城, 恵利子 and 大城, 吉秀 and Ito, Etsuo and Kayo, Kiyomi and Arakaki, Yusei and Morioka, Takamitu and Miyagi, Eriko and Oshiro, Yoshihide},
 issue = {4},
 journal = {琉球医学会誌 = Ryukyu Medical Journal},
 month = {},
 note = {Many old people in Okinawa have been suffering from chronic obstructive lung diseases and the incidence of lung cancer is higher than that of main land Japan. The presumable cause of such respiratory disorders, might be the prolonged inhalation of fine particles of siltstone, an ingredient of the special soil of Okinawa named Jaagal (Locally called Kucha), which has been damaging the lung tissues. The Jaagal contains large amount of siltstone and is found mostly in the southern part of the main island. Moreover, strong seasonal winds create dust in these areas which blow into the houses, leading to inhalation by the dwellers. To probe this hypothesis and the toxic effects of siltstone particles to the lung, some attempts were made to induce experimental pneumoconiosis in the lung of ICR strain mice by the inhalation of the siltstone powder. The lungs showed congestion, edema and hemorrhage after two weeks from the start of the experiment, while deposition of the siltstone in the lung tissue were observed after four weeks. The nodular lesions consisted of macrophages with phagocytized siltstone particles, epithelioid cells, fibroblasts and lymphocyte infiltration were formed at 5 - 6 weeks after the beginning of the experiment. These findings seem to be the main results of this experiment and interpreted as the beginning of granuloma and fibrosis. These results indicate that the long-standing inhalation of the siltstone particles is harmful to the lung tissue., 論文},
 pages = {185--187},
 title = {[原著］沖縄の特殊土壌中のシルト岩粉末による実験塵肺症の試作},
 volume = {16},
 year = {1996}
}