{"created":"2022-02-22T04:14:48.999692+00:00","id":2016131,"links":{},"metadata":{"_buckets":{"deposit":"284089f1-9ce5-420c-9daf-1b3817b90c2e"},"_deposit":{"id":"2016131","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2016131"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02016131","sets":["1642838163960:1642838198944:1642838199408:1642838219712","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"[\u539f\u8457\uff3dA pilot study of docetaxel and TS-1 combination chemotherapy for advanced gastric cancer","subitem_1551255648112":"ja"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shimoji, Hideaki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nishimaki, Tadashi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Sunagawa, Hiroki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kuninaka, Kouichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Matsubara, Hirotaka","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_1522650717957":"ja","subitem_1522651041219":"\u7409\u7403\u533b\u5b66\u4f1a"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"docetaxel"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"TS-1"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"chemotherapy"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"gastric cancer"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"PURPOSE: The aim of this study was to assess the efficacy and safety of combination chemotherapy with docetaxel and TS-1. PATIENTS AND METHODS: Five patients with advanced gastric cancer were treated with a combination chemotherapy regimen consisting of docetaxel and TS-1. All patients had undergone prior chemotherapy. Docetaxel at a dose of 30 mg/m^2 was intravenously administered on Day 1 and 8, and TS-1 at a dose of 80mg/m^2 /day was orally administered for 2 weeks followed by 1 drug-free week. RESULTS: Three of the 5 patients showed a partial response, of a response rate of 60%. Two of the 5 patients had stable diseases. One patient experienced grade 3 leukocytopeniia, grade 2 diarrhea and grade 2 alopecia. In the other patients, only low grade toxicities (grade 1 or 2 leukocytopenia, neutrocytopenia and anemia) were seen. CONCLUSION: The combination chemotherapy of docetaxel and TS-1 was found to be effective and well tolerable by advanced gastric cancer patients. This combination may be useful as a second-line chemotherapy.","subitem_description_type":"Other"},{"subitem_description":"\u8ad6\u6587","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"\u7409\u7403\u533b\u5b66\u4f1a"},{"subitem_1522300295150":"en","subitem_1522300316516":"Ryukyu Medical Association"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"1346888X"},{"subitem_1522646500366":"ISSN","subitem_1522646572813":"0289-1530"},{"subitem_1522646500366":"NCID","subitem_1522646572813":"AN10369445"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"\u7409\u7403\u533b\u5b66\u4f1a\u8a8c = Ryukyu Medical Journal"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"24","bibliographicPageStart":"21","bibliographicVolumeNumber":"23"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"v23p21.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2016131/files/v23p21.pdf"},"version_id":"e9e5f435-bc5e-4fc2-b601-fb43b96eb3ea"}]},"item_title":"[\u539f\u8457\uff3dA pilot study of docetaxel and TS-1 combination chemotherapy for advanced gastric cancer","item_type_id":"15","owner":"1","path":["1642838219712","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-07-02"},"publish_date":"2010-07-02","publish_status":"0","recid":"2016131","relation_version_is_last":true,"title":["[\u539f\u8457\uff3dA pilot study of docetaxel and TS-1 combination chemotherapy for advanced gastric cancer"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-02-22T04:14:52.424927+00:00"}