{"created":"2022-02-22T04:15:11.675469+00:00","id":2016144,"links":{},"metadata":{"_buckets":{"deposit":"f5ebe436-9b49-4160-986f-d66e1c21a006"},"_deposit":{"id":"2016144","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2016144"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02016144","sets":["1642838163960:1642838198944:1642838199408:1642838221208","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"［原著］Hemoglobin as an important prognostic factor in concurrent chemoradiotherapy for locally advanced carcinoma of the cervix","subitem_title_language":"ja"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Toma, Takashi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nagai, Yutaka","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Moromizato, Hidehiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Toita, Takafumi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Murayama, Sadayuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kanazawa, Koji","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"琉球医学会","subitem_rights_language":"ja"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"cervical carcinoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"concurrent chemoradiotherapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hemoglobin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"prognosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Objective: To examine a possible association of hemoglobin with clinical outcome in patients with locally advanced squamous cell carcinoma of the cervix who were treated with concurrent chemoradiotherapy (CCRT). Methods: Seventy-five patients with Stage IB to IVA disease who were treated with CCRT were reviewed retrospectively. The mean age was 49.8 years. In the treatment, standard radiotherapy was performed accompanied by concomitant chemotherapy using cisplatin. Pre-treatment hemoglobin was defined as the earliest hemoglobin level prior to the initiation of treatment. Weekly nadir hemoglobin levels throughout treatment were averaged and used as average weekly nadir hemoglobin during treatment (AWNHg). The mean follow-up time was 28.6 months. Results: The mean pre-treatment hemoglobin of 11.6 g/dL was significantly reduced to the mean AWNHg of 9.9 g/dL. The levels of pre-treatment hemoglobin and AWNHg were significantly associated with tumor response to treatment. The 5-year cumulative diseasefree survival and overall survival rates for all 75 patients were 67.8% and 75.3%, respectively. Multivariate statistical analysis revealed that AWNHg (>=9.0 versus <9.0 g/dL) was an independent prognostic factor for overall survival (p=0.038), but pre-treatment hemoglobin was not a significant factor. Conclusion: AWNHg was one of the most powerful independent predictors of overall survival in patients undergoing CCRT for locally advanced squamous cell carcinoma of the cervix.","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"琉球医学会","subitem_publisher_language":"ja"},{"subitem_publisher":"Ryukyu Medical Association","subitem_publisher_language":"en"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"1346888X","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"0289-1530","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AN10369445","subitem_source_identifier_type":"NCID"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_source_title":"琉球医学会誌 = Ryukyu Medical Journal","subitem_source_title_language":"ja"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"10","bibliographicPageStart":"1","bibliographicVolumeNumber":"24"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"v24p1.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2016144/files/v24p1.pdf"},"version_id":"6677492b-f482-421d-9590-b98dc256294b"}]},"item_title":"［原著］Hemoglobin as an important prognostic factor in concurrent chemoradiotherapy for locally advanced carcinoma of the cervix","item_type_id":"15","owner":"1","path":["1642838221208","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-07-02"},"publish_date":"2010-07-02","publish_status":"0","recid":"2016144","relation_version_is_last":true,"title":["［原著］Hemoglobin as an important prognostic factor in concurrent chemoradiotherapy for locally advanced carcinoma of the cervix"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-10-31T07:51:15.617471+00:00"}