@article{oai:u-ryukyu.repo.nii.ac.jp:02016164, author = {Isa, Tsutomu and Miyazato, Hiroshi and Shimoji, Hideaki and Kusano, Toshiomi and Muto, Yoshihiro and Yamauchi, Kazuo}, issue = {1}, journal = {琉球医学会誌 = Ryukyu Medical Journal}, note = {We herein present four cases of xanthogranulomatous cholecystitis (XGC) that involved the adjacent structures and clinically mimicked carcinoma of the gallbladder (diffuse-infiltrating type). The patients consisted of two males and two females, with a mean age of 64.5 years (range, 51 to 77 years). Three of them had an episode of acute cholecystitis one to five months before the operation. An elevation of CA19-9 and Span-1 was recognized in one case. Gallstones were present in all cases with a thickening of the gallbladder wall on either ultrasonography (US) or computed tomography (CT). Furthermore, three cases revealed either intramural hyperechoic spots or comet-like echoes on US. Three cases were erroneously diagnosed as carcinoma based on the operative findings and underwent a cholecystectomy with a partial hepatic resection of the gallbladder bed and/or a resection of the surrounding structures involved. In the remaining case, an intraoperative pathological study revealed chronic inflammation without malignancy and a cholecystectomy was thus performed. The resected gallbladders histologically revealed many granulomas (abundant pigment-laden foamy histiocytes, fibroblasts and inflammatory cells) which extended to the liver and/or colon. Therefore, in such a situation, an intraoperative pathological study is recommended in order to avoid any excessive and unnecessary surgery when determining the optimal method of treatment., 論文}, pages = {25--29}, title = {[症例報告]Xanthogranulomatous cholecystitis mimicking carcinoma of the gallbladder : Report of four cases}, volume = {20} }