{"_buckets": {"deposit": "845e8513-e34c-4a85-b09e-154380fd852a"}, "_deposit": {"id": "2016208", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "2016208"}, "status": "published"}, "_oai": {"id": "oai:u-ryukyu.repo.nii.ac.jp:02016208", "sets": ["1642838216134", "1642838412624"]}, "author_link": [], "item_1617186331708": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "[\u7dcf\u8aac\uff3dI\u578b\u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u304a\u3051\u308bIgE\u3068\u305d\u306e\u53d7\u5bb9\u4f53Fc$ \\varepsilon $RI\u306e\u76f8\u4e92\u53cd\u5fdc", "subitem_1551255648112": "ja"}, {"subitem_1551255647225": "Interaction between IgE and its receptor (Fc$ \\varepsilon $RI) in type-I allergy", "subitem_1551255648112": "en"}]}, "item_1617186419668": {"attribute_name": "Creator", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u82b1\u57ce, \u548c\u5f66", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "\u6e21\u6176\u6b21, \u8cc0\u535a", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "\u5cf6\u7530, \u8aa0\u4e8c", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "\u7802\u5ddd, \u660c\u7bc4", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "\u4e2d\u6751, \u771f\u7406\u5b50", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "\u5c0f\u6749, \u5fe0\u8aa0", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "Hanashiro, Kazuhiko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Tokeshi, Yoshihiro", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Shimada, Seiji", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Sunagawa, Masanori", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Nakamura, Mariko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kosugi, Tadayoshi", "creatorNameLang": "en"}]}]}, "item_1617186476635": {"attribute_name": "Access Rights", "attribute_value_mlt": [{"subitem_1522299639480": "open access", "subitem_1600958577026": "http://purl.org/coar/access_right/c_abf2"}]}, "item_1617186499011": {"attribute_name": "Rights", "attribute_value_mlt": [{"subitem_1522650717957": "ja", "subitem_1522651041219": "\u7409\u7403\u533b\u5b66\u4f1a"}]}, "item_1617186609386": {"attribute_name": "Subject", "attribute_value_mlt": [{"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "Type-I allergy"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "IgE-mediated inflammation"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "Fc$ \\varepsilon $RI"}]}, "item_1617186626617": {"attribute_name": "Description", "attribute_value_mlt": [{"subitem_description": "The type-I allergy is mediated by the interaction between IgE and its high affinity receptor (Fc$ \\varepsilon $RI) followed by cross-linking with specific allergen. The binding site for the IgE was identified on the Fc$ \\varepsilon $RI $ \\alpha $ subunit, and the soluble $ \\alpha $ subunit of Fc$ \\varepsilon $RI was effective in controlling the lgE-mediated inflammation. Recent studies using IgE knock out mice revealed that IgG could also induce anaphylaxis. However, in the Fc$ \\varepsilon $RI $ \\alpha $ subunit knock out mice, IgE and IgG could not induce anaphylaxis. These results demonstrated that Fc$ \\varepsilon $RI expression is essential for the development of the IgE-mediated inflammation. Further investigation on the interaction between IgE and Fc$ \\varepsilon $Rl $ \\alpha $ subunit on the membrane of target cells and on signal transduction in the cytoplasma and nucleus should offer novel concepts in developing strategies for the treatment of IgE-mediated inflammation.", "subitem_description_type": "Other"}, {"subitem_description": "\u8ad6\u6587", "subitem_description_type": "Other"}]}, "item_1617186643794": {"attribute_name": "Publisher", "attribute_value_mlt": [{"subitem_1522300295150": "ja", "subitem_1522300316516": "\u7409\u7403\u533b\u5b66\u4f1a"}, {"subitem_1522300295150": "en", "subitem_1522300316516": "Ryukyu Medical Association"}]}, "item_1617186702042": {"attribute_name": "Language", "attribute_value_mlt": [{"subitem_1551255818386": "jpn"}]}, "item_1617186920753": {"attribute_name": "Source Identifier", "attribute_value_mlt": [{"subitem_1522646500366": "ISSN", "subitem_1522646572813": "1346888X"}, {"subitem_1522646500366": "ISSN", "subitem_1522646572813": "0289-1530"}, {"subitem_1522646500366": "NCID", "subitem_1522646572813": "AN10369445"}]}, "item_1617186941041": {"attribute_name": "Source Title", "attribute_value_mlt": [{"subitem_1522650068558": "ja", "subitem_1522650091861": "\u7409\u7403\u533b\u5b66\u4f1a\u8a8c = Ryukyu Medical Journal"}]}, "item_1617187056579": {"attribute_name": "Bibliographic Information", "attribute_value_mlt": [{"bibliographicIssueNumber": "3", "bibliographicPageEnd": "127", "bibliographicPageStart": "117", "bibliographicVolumeNumber": "20"}]}, "item_1617258105262": {"attribute_name": "Resource Type", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_1617265215918": {"attribute_name": "Version Type", "attribute_value_mlt": [{"subitem_1522305645492": "VoR", "subitem_1600292170262": "http://purl.org/coar/version/c_970fb48d4fbd8a85"}]}, "item_1617605131499": {"attribute_name": "File", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "download_preview_message": "", "file_order": 0, "filename": "v20p117.pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "", "size": 0, "url": {"objectType": "fulltext", "url": "https://u-ryukyu.repo.nii.ac.jp/record/2016208/files/v20p117.pdf"}, "version_id": "03e265d9-d6d2-4cd4-8983-5723f88d3163"}]}, "item_title": "[\u7dcf\u8aac\uff3dI\u578b\u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u304a\u3051\u308bIgE\u3068\u305d\u306e\u53d7\u5bb9\u4f53Fc$ \\varepsilon $RI\u306e\u76f8\u4e92\u53cd\u5fdc", "item_type_id": "15", "owner": "1", "path": ["1642838216134", "1642838412624"], "permalink_uri": "http://hdl.handle.net/20.500.12000/0002016208", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2010-07-02"}, "publish_date": "2010-07-02", "publish_status": "0", "recid": "2016208", "relation": {}, "relation_version_is_last": true, "title": ["[\u7dcf\u8aac\uff3dI\u578b\u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u304a\u3051\u308bIgE\u3068\u305d\u306e\u53d7\u5bb9\u4f53Fc$ \\varepsilon $RI\u306e\u76f8\u4e92\u53cd\u5fdc"], "weko_shared_id": -1}