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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球医学会誌
  4. 29巻3・4号
  1. 部局別インデックス
  2. その他

[原著]Evaluation of delayed cervical lymph node metastasis in T1/2 squamous cell carcinoma of the tongue

http://hdl.handle.net/20.500.12000/0002016241
http://hdl.handle.net/20.500.12000/0002016241
d7565871-0225-457d-9f52-bb07650a9a88
名前 / ファイル ライセンス アクション
v29(3,4)p31.pdf v29(3,4)p31.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2012-04-13
タイトル
タイトル [原著]Evaluation of delayed cervical lymph node metastasis in T1/2 squamous cell carcinoma of the tongue
言語 ja
作成者 Matayoshi, Akira

× Matayoshi, Akira

en Matayoshi, Akira

Nakasone, Toshiyuki

× Nakasone, Toshiyuki

en Nakasone, Toshiyuki

Kina, Shinichiro

× Kina, Shinichiro

en Kina, Shinichiro

Arakaki, Keiichi

× Arakaki, Keiichi

en Arakaki, Keiichi

Takemoto, Hiroyuki

× Takemoto, Hiroyuki

en Takemoto, Hiroyuki

Liang, Feixin

× Liang, Feixin

en Liang, Feixin

Phonaphonh, Thongsavanh

× Phonaphonh, Thongsavanh

en Phonaphonh, Thongsavanh

Kuang, Hai

× Kuang, Hai

en Kuang, Hai

Sunakawa, Hajime

× Sunakawa, Hajime

en Sunakawa, Hajime

又吉, 亮

× 又吉, 亮

ja 又吉, 亮

喜名, 振一郎

× 喜名, 振一郎

ja 喜名, 振一郎

新垣, 敬一

× 新垣, 敬一

ja 新垣, 敬一

嵩元, 裕之

× 嵩元, 裕之

ja 嵩元, 裕之

砂川, 元

× 砂川, 元

ja 砂川, 元

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 squamous cell carcinoma of the tongue
言語 en
主題Scheme Other
主題 delayed cervical lymph node metastasis
言語 en
主題Scheme Other
主題 immunohistochemistry
言語 en
主題Scheme Other
主題 lymphatic vessel density
言語 en
主題Scheme Other
主題 receiver operating characteristic curve
内容記述
内容記述タイプ Other
内容記述 Purpose : To predict the risk of delayed cervical lymph node metastasis (delayed-CLN-met) in T1/2 squamous cell carcinoma (SCC) of the tongue, clinicopathological and immunohistochemical characteristics of cervical lymph node metastasis (CLN-met) cases were compared to those negative for cervical lymph node (neg-CLN) involvement. Methods : Clinical characteristics, histopathological parameters, intratumoral lymphatic vessel density (LVD), and intratumoral microvessel density (MVD) were evaluated in 54 patients with T1/2 SCC of the tongue. LVD and MVD were determined by immunohistochemical staining using D2-40 and CD34 antibodies, respectively. Results Parameters significantly correlated with lymph node metastases included T classification (P = 0.0013) and muscle invasion (P = 0.0045). In CLN-met cases, the LVD was significantly higher (P = 0.0003) compared with neg-CLN cases. MVD was not statistically different (P = 0.39) in CLN-met cases compared with neg-CLN cases. Results of multivariate logistic regression analysis for CLN-met showed that T classification and LVD were independent risk factors for CLN-met. Although results of multivariate logistic regression analysis for delayed-CLN-met was not statistically significant, LVD had a tendency to be a risk factor for delayed-CLN-met in univariate analysis (P = 0.05). The depth of SCC invasion into the muscle layer (depth-IM) was statistically significant (P = 0.002). Conclusions : LVD and T classification were independent risk factors for CLN-met; however, in predicting delayed-CLN-met, whether tumor invades to the muscle layer was only a risk factor in T1/2 SCC of the tongue. Although LVD was not statistically significant to predict delayed-CLN-met, LVD had a tendency to be a risk factor for delayed-CLN-met. Cases with depth-IM of > 2 mm and high LVD are thought to be at high risk of delayed-CLN-met in stage 1/2 SCC of the tongue.
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球医学会
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1346-888X
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子タイプ NCID
収録物識別子 AN10369445
収録物名
言語 ja
収録物名 琉球医学会誌 = Ryukyu Medical Journal
書誌情報
巻 29, 号 3・4, p. 31-38
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