{"created":"2022-02-22T04:44:09.795363+00:00","id":2016244,"links":{},"metadata":{"_buckets":{"deposit":"94c9403d-4ccd-4a0e-b771-637b2511b58b"},"_deposit":{"id":"2016244","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2016244"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02016244","sets":["1642838163960:1642838198944:1642838199408:1642838227712","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"[依頼総説]血液悪性疾患と脂質代謝異常 －低 HDL-C 血症合併の検討－","subitem_1551255648112":"ja"},{"subitem_1551255647225":"Dyslipidemia in hematological malignancies : analysis of hypo-HDL cholesterolemia","subitem_1551255648112":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小宮, 一郎","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"平良, 伸一郎","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"友寄, 毅昭","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"池間, 朋己","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"益崎, 裕章","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"Komiya, Ichiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Taira, Shin-ichiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Tomoyose, Takeaki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ikema, Tomomi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Masuzaki, Hiroaki","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_1522650717957":"ja","subitem_1522651041219":"琉球医学会"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"Hematological malignancies"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"HDL-C"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"LDL-C"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"cytokines"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Low concentrations of high-density lipoprotein cholesterol (HDL-C) or low-density lipoprotein cholesterol (LDL-C) were reported in patients with hematological malignancies and other malignant tumors. Increased cytokines might induce the uptake of LDL-C and HDL-C, and decrease plasma lecithin-cholesterol acyltransferase (LCAT) activity and lipoprotein lipase (LPL) activity, resulting in low serum cholesterol and high serum TG levels. Compared our patients with malignant lymphoma (ML) and adult Tcell leukemia-lymphoma (ATLL) with normal controls, low HDL-C (less than 40 mg/dL) was observed in 60.3% of patients and in 6.2% of controls, and low LDL-C (less than 80mg /dL) was observed in 20.5% of patients and in 9.1% of controls. Lower HDL-C levels were associated with a poorer clinical outcome. Cytokine-induced low HDL-C indicated the disease activity and the prognosis in patients with hematological malignancies","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"琉球医学会"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"jpn"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"1346-888X"},{"subitem_1522646500366":"ISSN","subitem_1522646572813":"0289-1530"},{"subitem_1522646500366":"NCID","subitem_1522646572813":"AN10369445"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"琉球医学会誌 = Ryukyu Medical Journal"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueNumber":"1-4","bibliographicPageEnd":"19","bibliographicPageStart":"13","bibliographicVolumeNumber":"30"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"v30(1-4)p13.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2016244/files/v30(1-4)p13.pdf"},"version_id":"76f15312-b325-4864-9a4a-6672b4ce4706"}]},"item_title":"[依頼総説]血液悪性疾患と脂質代謝異常 －低 HDL-C 血症合併の検討－","item_type_id":"15","owner":"1","path":["1642838227712","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2012-12-11"},"publish_date":"2012-12-11","publish_status":"0","recid":"2016244","relation_version_is_last":true,"title":["[依頼総説]血液悪性疾患と脂質代謝異常 －低 HDL-C 血症合併の検討－"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-02-22T04:44:12.977361+00:00"}