@article{oai:u-ryukyu.repo.nii.ac.jp:02016267, author = {大浦, 孝 and 河上, 好秀 and 山本, 誠 and 奥田, 治爾 and Oura, Takashi and Kawakami, Yoshihide and Yamamoto, Makoto and Okuda, Koji}, issue = {4}, journal = {琉球大学保健学医学雑誌=Ryukyu University Journal of Health Sciences and Medicine}, note = {We reported a case of allergic granulomatous angiitis (AGA). A 37-year-old female patient was admitted to our clinic for closer examination of gait disturbance. She suffered from bronchial asthma for the past four years, but the attacks had ceased since the appearance of this symptom. In physical examination, her tendon reflex was depressed in the upper extremities and was absent in the lower extremities. Her grasping power was undetectable bilaterally. Sensory disturbance was apparent below the elbow and knee joints. Laboratory data indicated positive proteinuria as well as the presence of some RBC and hyaline cast in the urinary sediments. Leukocytosis was found while eosinophilia was prominent. ESR accelerated and CRP was positive. The histopathological observation of muscle biopsy revealed the presence of an inflammation around the small vessels and the prominent infiltration of eosinophils. After therapy began with the administering of adenal corticosteroid, both clinical symptoms and laboratory data showed improvement. Our cas was diagnosed as AGA which was differentiated from Periarteritis nodosa (PN) as a new clinical entity by Churg and Strauss in 1951. AGA is characterized by bronchial asthma followed by general symptoms and eosinophilia as well as, histopathologically, necrotizing angiitis and granuloma formation. This disease is so rare that only a few cases have been reported in Japan. Finally, we discussed about similar diseases related to PN., 論文}, pages = {372--380}, title = {[原著]Allergic granulomatous angiitis の1例}, volume = {3} }