{"created":"2022-02-22T04:45:11.350251+00:00","id":2016277,"links":{},"metadata":{"_buckets":{"deposit":"6ca355fe-cae6-41fb-90a6-3ca0259a8422"},"_deposit":{"id":"2016277","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2016277"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02016277","sets":["1642838163960:1642838198944:1642838242961:1642838243524","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"[原著]コルポスコピーによる子宮頸癌初期病変の診断","subitem_1551255648112":"ja"},{"subitem_1551255647225":"Diagnostic Colposcopy of the Earliest Cancers of the Cervix Uteri","subitem_1551255648112":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"東, 政弘","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"竹中, 静広","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"有村, 徹","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"永山, 孝","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"仲地, 広順","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"野原, 雄介","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"Higashi, Masahiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Takenaka, Shizuhiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Arimura, Toru","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nagayama, Takashi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nakachi, Hiromasa","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nohra, Yusuke","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_1522650717957":"ja","subitem_1522651041219":"琉球医学会"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Diagnostic conization has been the routine method of investigation of abnormal cervical smears. Obvious drawbacks to the conization include hospitalization, morbidity, possible interference with future fertility, and less satisfactory sampling in the pregnant patient. For these reasons, this operation should be performed only when necessary in establishing a correct diagnosis. Making acorrect diagnosis without conization is difficult, but can be done by evaluating the results of colposcopic appearance and directed punch biopsy in combination with cytology. The purpose of this study is to prove the accuracy of colposcopy, directed biopsy and cytology, thus reducing the need for diagnostic conization. A total of 233 patients, refered to our department because of suspicious or abnormal smears, were treated from August 1975 to September 1977. These patients were utilized for this preliminary study. A colposcopic diagnosis was made by reference to easily observable features of surface pattern, vascular pattern, cor tone, opacity and gland openings. We classified these findings retrospectively and found colposcopic characteristics peculiar to each lesion of the cervix. Out of 233 patients, 88 patients were not conized because they were diagnosed by directed biopsy and colposcopy as having cervicitis or mild dysplasia. By performing conization or hysterectomy on the remaining 145 patients, 6 cases were diagnosed as mild dysplasia, 14 cases as severe dysplasia, 67 cases as carcinoma in situ (CIS), 42 cases as microinvasive carcinoma and 16 cases as frank invasive carcinoma. The results of the colposcopic impression and the directed biopsy were combined to formulate a single diagnosis, called colposcopic evaluation'. The diagnosis made jointly by colposcopy, directed biopsy and cytology was called pre-treatment diagnosis. The final histological diagnosis was compared with the results of colposcopic appearance, directed biopsy, colposcopic evaluation and then with the pre-treatment diagnosis. The accuracy of colposcopy  was 39.1% in severe dysplasia, 73.2% in CIS and 73.5% in microinvasive carcinoma. The accuracy of directed biopsy was 40.7% in severe dysplasia, 75.4% in CIS and 86.4% in microinvasive carcinoma. The accuracy of colposcopic evaluation was 66.7% in severe dysplasia, 78.9% in CIS and 72.2% in microinvasive carcinoma. The accuracy of pretreatment diagnosis was 66.7% in severe dysplasia, 73.2% in CIS and 63.6% in microinvasive carcinoma. The correlation between the pre-treatment diagnosis and the final histological diagnosis was clinically accurate in 94 cases (70.8%); histology was less advanced than expected in 26 cases (19.5%) and more advanced than expected in 13 cases (9.8%). The recognized falsenegative rate of directed biopsy in this study (more than 1 histologic degree in the surgical specimen than the directed biopsy was 9 cases (6.8%) among 133 patients.","subitem_description_type":"Other"},{"subitem_description":"The false-negative rate of colposcopy alone, colposcopic evaluation and pretreatment diagnosis were 6.2%, 0.75% and 0.75% respectively. From the results of this study we conclude that we could make a correct diagnosis without conization, by colposcopic evaluation (both colposcopic appearance and directed biopsy) and pre-treatment diagnosis (combining colposcopic evaluation with cytology).","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"琉球大学保健学部"},{"subitem_1522300295150":"en","subitem_1522300316516":"College of Health Sciences, University of the Ryukyus"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"jpn"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"ISSN","subitem_1522646572813":"0285-9270"},{"subitem_1522646500366":"NCID","subitem_1522646572813":"AN00250763"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"琉球大学保健学医学雑誌＝Ryukyu University Journal of Health Sciences and Medicine"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueNumber":"1","bibliographicPageEnd":"66","bibliographicPageStart":"59","bibliographicVolumeNumber":"1"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"v1p59.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2016277/files/v1p59.pdf"},"version_id":"913efe47-3cad-46bf-ae7f-874dac868c36"}]},"item_title":"[原著]コルポスコピーによる子宮頸癌初期病変の診断","item_type_id":"15","owner":"1","path":["1642838243524","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-07-18"},"publish_date":"2014-07-18","publish_status":"0","recid":"2016277","relation_version_is_last":true,"title":["[原著]コルポスコピーによる子宮頸癌初期病変の診断"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-02-22T04:45:14.808006+00:00"}