@article{oai:u-ryukyu.repo.nii.ac.jp:02016374, author = {Kajiwara, Keizo and Mimura, Goro}, issue = {1}, journal = {琉球大学保健学医学雑誌=Ryukyu University Journal of Health Sciences and Medicine}, note = {Until the present, essential hypertension has presumed as a hereditary desease from the results of the study of families and twins (Weitz, 1923; Allan, 1933; Ayman, 1934; Hines, 1937; Platt, 1947, 1961; Miyao, Mimura, Terai, 1968). The comparison between monozygotic (MZ) twins and dizygotic (DZ) twins offers a convenient means for studying some problems of human heredity. Aa the results of previous genetic study of essential hypertension, it can be presumed that hypertension is transmitted by a mendelian dominant one-gene (Weitz,1923; Ayman, 1934; Miyao, 1953), therefore, this disease has been regarded as a clinical entity of qualitative character. But according to our recent genetic study and other investigators' results (Oshiro, 1964; Miyao, Mimura, Terai, 1968; Hamilton, Pickerling, Roberts, Sowrg, 1954), it has become apparent that blood pressure is a continuous character. If blood pressure, genetically, is a quantitative character, to classify blood pressure into hypertension, normotension and hypertension respectively at a certain level as a different qualitative character is questionable. But from the clinical points of view, hypertension will be diagnosed in the case of excessive blood pressure at a certain level, nevertheless blood pressure is a continuous character. One of the authors, Mimnra, reported the study of twins with hypertension, in 1973, on the basis of the mentioned opinion. In this paper, I'd like to state the average difference of blood pressure between MZ and DZ twins, the difference of blood pressure of MZ twins induced by the difference of environment, and the difference of concordance rate of hypertension between MZ and DZ twins, moreover, the difference of concordance rate of cerebrovascular disease between MZ and DZ twins., 論文}, pages = {8--16}, title = {[原著]Study on Twins with Hypertension and Cerebrovascular Disease in Japan}, volume = {2} }