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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球大学保健学医学雑誌
  4. 3巻1号
  1. 部局別インデックス
  2. その他

[原著]Effects of dipeptides containing L-glutamic acid on the excitability of identifiable giant neurones of the African giant snail (Achatina fulica Ferussac).

http://hdl.handle.net/20.500.12000/0002016389
http://hdl.handle.net/20.500.12000/0002016389
0845c551-1d38-4a83-ba4b-3f776349e74b
名前 / ファイル ライセンス アクション
v3p1.pdf v3p1.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2014-07-18
タイトル
タイトル [原著]Effects of dipeptides containing L-glutamic acid on the excitability of identifiable giant neurones of the African giant snail (Achatina fulica Ferussac).
言語 ja
作成者 Endo, Iwao

× Endo, Iwao

en Endo, Iwao

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Tamura, Hiroko

× Tamura, Hiroko

en Tamura, Hiroko

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Takeuchi, Hiroshi

× Takeuchi, Hiroshi

en Takeuchi, Hiroshi

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Takehara, Hiroo

× Takehara, Hiroo

en Takehara, Hiroo

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
内容記述
内容記述タイプ Other
内容記述 In a fine series of pioneering works, Kakimoto, Kanazawa, Nakajima, Sano et al.^<1-6)> reported the presence of many dipeptides, especially those containing L-glutamic acid, in the mammalian central nervous systems. However, the physiological roles of these peptides have not yet been investigated. Takeuchi, Tamura et al^<15-18)> demonstrated using the two identifiable giant neurones (TAN, tonically autoactive neurone and PON, periodically oscillating neurone) of the Afncan giant snail (Achatina fulica Ferussac) that the two aromatic dipeptides, L-Phe-L-Tyr and LPhe-L-Trp, had a marked inhibitory effect on neuronal excitability, and that the tripeptide, $ \gamma $-LGlu-L-Phe-L-Tyr, had a stronger effect than the two aromatic dipeptides mentioned above. Besides, it was also reported by Takeuchi, Yokoi et al.^<20, 22-24)> that some derivatives of L-glutamic acid (L-Glu), for example, erythro-$ \beta $ hydroxy-L-Glu, had a remarkable inhibitory effect, although neither LGlu nor D-Glu had any effect on the same neurone. In the present study, we examined effects of L-Glu-containing dipeptides on the excitability of the two identifiable giant neurones (TAN and PON) of Achatina fulica Ferussac Some of the dipeptides examined have been demonstrated to exist in the central nervous systems.
内容記述
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球大学保健学部
出版者
言語 en
出版者 College of Health Sciences, University of the Ryukyus
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0285-9270
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AN00250763
収録物名
言語 ja
収録物名 琉球大学保健学医学雑誌=Ryukyu University Journal of Health Sciences and Medicine
書誌情報
巻 3, 号 1, p. 1-8
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