@article{oai:u-ryukyu.repo.nii.ac.jp:02016488, author = {武藤, 良弘 and 正, 義之 and 外間, 章 and 山内, 和雄 and 栗原, 公太郎 and 山里, 将仁 and 日高, 修 and 甲斐田, 和雄 and 内村, 正幸 and 脇, 慎治 and 鮫島, 恭彦 and 山田, 護 and Muto, Yoshihiro and Sho, Yoshiyuki and Hokama, Akira and Yamauchi, Kazuo and Kurihara, Kotaro and Yamazato, Masahito and Hidaka, Osamu and Kaieda, Kazuhiro and Uchimura, Masayuki and Waki, Shinji and Sameshima, Yasuhiko and Yamada, Mamoru}, issue = {2}, journal = {琉球大学保健学医学雑誌=Ryukyu University Journal of Health Sciences and Medicine}, note = {A case of a 75 year - old female with mucosal carcinoma of the gallbladder in cholecystoduodenal fistula was described, and then the resected gallbladders in twenty one cases of biliary enteric fistula were histologically studied to investigate their morphological features, and discuss relation between fistula and genesis of gallbladder cancer. The gallbladders were small in size and contracted. The walls of the gllabladders were thickened. Histologically, they showed inflammatory changes ( fibrous thickening of the wall, inflammatory infiltrates and intimal thickening of the artery ) that were characteristic in this disease. On the other hand, the mucosa was relatively well preserved. It revealed mucous gland metaplasia in 95.2 per cent and goblet cell metaplasia in 52.4 per cent. The incidence of metaplasia was similar to that in patients with cholelithiasis, and lower than that in gallbladder cancer patients. Based on these results, reflux of enteric contents into the gallbladder may cause persistent inflammation of the gallbladder, but may not correlate to the genesis of the gallbladder cancer., 論文}, pages = {133--142}, title = {[原著]内胆汁瘻症例 : 胆嚢病変の組織学的検討}, volume = {5} }