{"created":"2022-02-22T07:20:01.596585+00:00","id":2016921,"links":{},"metadata":{"_buckets":{"deposit":"31db5165-a5ac-495f-bf0d-0ba3b01ab490"},"_deposit":{"id":"2016921","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2016921"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02016921","sets":["1642838163960:1642838198944:1642838199408:1642838232560","1642838403551:1642838412624"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Psychopathology and clinical outcomes of first-visit outpatients under 20 years old exhibiting a psychotic state","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ishibashi, Takao","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Shinzato, Hotaka","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Zamami, Yu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Shimabukuro, Morihiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kondo, Tsuyoshi","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"琉球医学会","subitem_rights_language":"ja"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"under 20","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"schizophrenia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"at risk mental state","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"early symptoms","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"insight","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"outcome of patients under 20 years old exhibiting a psychotic state. Methods: Forty-five patients (15 males and 30 females) under 20 years old with a diagnostic description of psychosis, schizophrenia, at-risk mental state (ARMS) or psychotic-like experiences, who had first visited our clinic between January 2012 and December 2017 were retrospectively extracted from medical records. Their age at the onset of symptoms; psychiatric diagnoses, including comorbidities; insight of disease; symptomatology (early, positive, negative, catatonic and anxiety-depression symptoms); course of illness; prescribed medication; and final treatment outcome were investigated from various aspects. Results: Prodromal stages of schizophrenia (ARMS and early schizophrenia) were observed in about one-third of the overall patients. Patients with insight of disease had a higher baseline global assessment of functioning and greater number of early schizophrenic symptoms and anxiety-depression symptoms than those without insight of disease. In particular, early schizophrenic symptoms appear to be a discriminating factor for insight of disease. A total of 36.4% of ARMS patients converted to schizophrenia, while 25% of early schizophrenia patients converted to frank schizophrenia. Doses of antipsychotics (chlorpromazine equivalence: mg/day) were lower in ARMS non-converters (100±63) than in ARMS converters (364±44) or schizophrenics (477±337). Among overall patients, 62.3% showed improvement as the final treatment outcome. The global assessment of functioning values were higher at 6 (54.2%±17.2%) and 12 months (55.1%±18.9%) than that at baseline (34.1%±10.3%). Conclusion: The present study suggests that clinicians need to actively ask about early symptoms or attenuated positive symptoms in patients under 20 years old with a psychotic state who may still have insight of disease and encourage voluntary help-seeking. The first six months might be a critical period for achieving symptomatological remission and functional recovery in these patients.","subitem_description_type":"Other"},{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"琉球医学会","subitem_publisher_language":"ja"},{"subitem_publisher":"Ryukyu Medical Association","subitem_publisher_language":"en"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"1346-888X","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AN10369445","subitem_source_identifier_type":"NCID"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_source_title":"琉球医学会誌 = Ryukyu Medical Journal","subitem_source_title_language":"ja"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueNumber":"1-4","bibliographicPageEnd":"40","bibliographicPageStart":"29","bibliographicVolumeNumber":"39"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"Vol39p29.pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2016921/files/Vol39p29.pdf"},"version_id":"b63bc882-28c4-40ec-a995-78b895c53f50"}]},"item_title":"Psychopathology and clinical outcomes of first-visit outpatients under 20 years old exhibiting a psychotic state","item_type_id":"15","owner":"1","path":["1642838232560","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-11-18"},"publish_date":"2021-11-18","publish_status":"0","recid":"2016921","relation_version_is_last":true,"title":["Psychopathology and clinical outcomes of first-visit outpatients under 20 years old exhibiting a psychotic state"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-02-22T07:20:06.138395+00:00"}