{"created":"2022-06-13T03:25:18.899735+00:00","id":2018037,"links":{},"metadata":{"_buckets":{"deposit":"fe178cdc-6a9c-445f-9c7e-40365df4caf1"},"_deposit":{"created_by":8,"id":"2018037","owner":"8","owners":[8],"owners_ext":{"displayname":"ryukyu_lib","username":null},"pid":{"revision_id":0,"type":"depid","value":"2018037"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02018037","sets":["1642838158423:1642838158860:1642838159351","1642838403551:1642838409905"]},"author_link":[],"control_number":"2018037","item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"Psychopathology and clinical outcomes of first-visit outpatients under 20 years old exhibiting a psychotic state","subitem_1551255648112":"en"},{"subitem_1551255647225":"精神病状態を呈した20歳未満の外来初診患者の精神病理と臨床転帰","subitem_1551255648112":"ja"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"石橋, 孝勇","creatorNameLang":"ja"},{"creatorName":"Ishibashi, Takao","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_1522299639480":"open access","subitem_1600958577026":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"under 20"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"schizophrenia"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"at risk mental state"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"early symptoms"},{"subitem_1522299896455":"en","subitem_1522300014469":"Other","subitem_1523261968819":"insight"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Aim: This study aimed to clarify the psychopathology, global functioning and clinical outcome of patients under 20 years old exhibiting a psychotic state. Methods: Forty-five patients (15 males and 30 females) under 20 years old with a diagnostic description of psychosis, schizophrenia, at-risk mental state (ARMS) or psychotic-like experiences, who had first visited our clinic between January 2012 and December 2017 were retrospectively extracted from medical records. Their age at the onset of symptoms; psychiatric diagnoses, including comorbidities; insight of disease; symptomatology (early, positive, negative, catatonic and anxiety-depression symptoms); course of illness; prescribed medication; and final treatment outcome were investigated from various aspects. Results: Prodromal stages of schizophrenia (ARMS and early schizophrenia) were observed in about one-third of the overall patients. Patients with insight of disease had a higher baseline global assessment of functioning and greater number of early schizophrenic symptoms and anxiety-depression symptoms than those without insight of disease. In particular, early schizophrenic symptoms appear to be a discriminating factor for insight of disease. A total of 36.4% of ARMS patients converted to schizophrenia, while 25% of early schizophrenia patients converted to frank schizophrenia. Doses of antipsychotics (chlorpromazine equivalence: mg/day) were lower in ARMS non-converters (100 ± 63) than in ARMS converters (364 ± 44) or schizophrenics (477 ± 337). Among overall patients, 62.3% showed improvement as the final treatment outcome. The global assessment of functioning values were higher at 6 (54.2% ± 17.2%) and 12 months (55.1% ± 18.9%) than that at baseline (34.1% ± 10.3%). \nConclusion: The present study suggests that clinicians need to actively ask about early symptoms or attenuated positive symptoms in patients under 20 years old with a psychotic state who may still have insight of disease and encourage voluntary help-seeking. The first six months might be a critical period for achieving symptomatological remission and functional recovery in these patients.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_1522300295150":"ja","subitem_1522300316516":"琉球大学"},{"subitem_1522300295150":"en","subitem_1522300316516":"University of the Ryukyus"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_1551255818386":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_1522646500366":"PISSN","subitem_1522646572813":"1346-888X"},{"subitem_1522646500366":"NCID","subitem_1522646572813":"AN10369445"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_1522650068558":"ja","subitem_1522650091861":"琉球医学会誌 = Ryukyu Medical Journal"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueNumber":"1-4","bibliographicPageEnd":"40","bibliographicPageStart":"29","bibliographicVolumeNumber":"39"}]},"item_1617187087799":{"attribute_name":"Dissertation Number","attribute_value_mlt":[{"subitem_1551256171004":"甲第542号"}]},"item_1617187112279":{"attribute_name":"Degree Name","attribute_value_mlt":[{"subitem_1551256126428":"博士(医学)","subitem_1551256129013":"ja"}]},"item_1617187136212":{"attribute_name":"Date Granted","attribute_value_mlt":[{"subitem_1551256096004":"2022-03-18"}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_1522305645492":"VoR","subitem_1600292170262":"http://purl.org/coar/version/c_970fb48d4fbd8a85"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_1522306287251":{"subitem_1522306382014":"HDL","subitem_1522306436033":"http://hdl.handle.net/20.500.12000/0002018035"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-06-13"}],"filename":"iken542abstract.pdf","filesize":[{"value":"1.3 MB"}],"mimetype":"application/pdf","url":{"objectType":"abstract","url":"https://u-ryukyu.repo.nii.ac.jp/record/2018037/files/iken542abstract.pdf"},"version_id":"8a6114e5-1999-4509-9634-8cdfa1b7a185"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-06-13"}],"filename":"iken542review.pdf","filesize":[{"value":"995 KB"}],"mimetype":"application/pdf","url":{"objectType":"other","url":"https://u-ryukyu.repo.nii.ac.jp/record/2018037/files/iken542review.pdf"},"version_id":"359fd4e6-1f6d-4451-b583-74d3f89dc9ff"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-06-13"}],"filename":"iken542text.pdf","filesize":[{"value":"178 KB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2018037/files/iken542text.pdf"},"version_id":"8f2969c7-276e-45e8-9ef0-d8e9d75c13d3"}]},"item_1617944105607":{"attribute_name":"Degree Grantor","attribute_value_mlt":[{"subitem_1551256015892":[{"subitem_1551256027296":"18001","subitem_1551256029891":"kakenhi"}],"subitem_1551256037922":[{"subitem_1551256042287":"琉球大学","subitem_1551256047619":"ja"}]}]},"item_title":"Psychopathology and clinical outcomes of first-visit outpatients under 20 years old exhibiting a psychotic state","item_type_id":"59","owner":"8","path":["1642838159351","1642838409905"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-06-13"},"publish_date":"2022-06-13","publish_status":"0","recid":"2018037","relation_version_is_last":true,"title":["Psychopathology and clinical outcomes of first-visit outpatients under 20 years old exhibiting a psychotic state"],"weko_creator_id":"8","weko_shared_id":-1},"updated":"2022-06-13T04:54:51.395330+00:00"}