@phdthesis{oai:u-ryukyu.repo.nii.ac.jp:02018040, author = {今永, 直也 and Imanaga, Naoya}, note = {• PURPOSE: To elucidate clinical factors related to the presence of loculation of fluid (LOF) in the posterior choroid in central serous chorioretinopathy (CSC). • DESIGN: Retrospective, cross-sectional study. • METHODS: This single-center study included 158 eyes from 158 patients with CSC who were classified into LOF and non-LOF groups. The groups were compared for age, sex, spherical equivalent, axial length, subfoveal choroidal thickness (SCT), and scleral thickness. Using swept-source optical coherence tomography (OCT), we determined the presence of LOF based on B-scan and enface images. Scleral thickness was measured 6 mm posterior to the scleral spur in 4 directions using anteriorsegment OCT. • RESULTS: The 158 eyes were classified into 98 eyes in the LOF group and 60 eyes in the non-LOF group. In univariable analyses, the LOF group was younger (P = .01) and had a higher male ratio (P = .03) and greater SCT (P < .001) than the non-LOF group. All scleral thicknesses at the superior, temporal, inferior, and nasal points were greater in the LOF group than in the non-LOF group (426.2 vs 395.1 μm, 445.7 vs 414.9 μm, 459.2 vs 428.8 μm, 445.4 vs 414.3 μm, all P < .05). Multivariable analyses found that SCT (odds ratio [OR] 1.02, 95% CI 1.01-1.02, P < .001) and mean scleral thickness (OR 1.02, 95% CI 1.02-1.03, P = .002) were significantly associated with the presence of LOF. • CONCLUSION: A thick choroid and thick sclera appeared to be related to the presence of LOF in CSC.}, school = {琉球大学}, title = {Clinical Factors Related to Loculation of Fluid in Central Serous Chorioretinopathy} }