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  1. 学術雑誌論文
  2. その他
  1. 部局別インデックス
  2. 医学研究科

Metabolic-Syndrome-Related Comorbidities in Narcolepsy Spectrum Disorders: A Preliminary Cross-Sectional Study in Japan

http://hdl.handle.net/20.500.12000/0002019345
http://hdl.handle.net/20.500.12000/0002019345
b357e508-c908-480e-8734-939f174f75cb
名前 / ファイル ライセンス アクション
ijerph-19-06285-v2.pdf ijerph-19-06285-v2.pdf (617 KB)
Item type 琉球大学リポジトリ登録用アイテムタイプ(1)
公開日 2022-07-01
タイトル
タイトル Metabolic-Syndrome-Related Comorbidities in Narcolepsy Spectrum Disorders: A Preliminary Cross-Sectional Study in Japan
言語 en
作成者 Futenma, Kunihiro

× Futenma, Kunihiro

en Futenma, Kunihiro

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Takaesu, Yoshikazu

× Takaesu, Yoshikazu

en Takaesu, Yoshikazu

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Nakamura, Masaki

× Nakamura, Masaki

en Nakamura, Masaki

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Hayashida, Kenichi

× Hayashida, Kenichi

en Hayashida, Kenichi

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Takeuchi, Noboru

× Takeuchi, Noboru

en Takeuchi, Noboru

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Inoue, Yuichi

× Inoue, Yuichi

en Inoue, Yuichi

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 en
権利情報 © 2022 by the authors.
権利情報
言語 en
権利情報Resource https://creativecommons.org/licenses/by/4.0/
権利情報 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
主題
言語 en
主題Scheme Other
主題 narcolepsy spectrum disorders
主題
言語 en
主題Scheme Other
主題 narcolepsy type 2
主題
言語 en
主題Scheme Other
主題 metabolic syndrome
主題
言語 en
主題Scheme Other
主題 orexin
主題
言語 en
主題Scheme Other
主題 HLA-DQB1*06:02
主題
言語 en
主題Scheme Other
主題 obesity
内容記述
内容記述タイプ Abstract
内容記述 Narcolepsy types 1 (NT1) and 2 (NT2) and idiopathic hypersomnia (IH) are thought to be a disease continuum known as narcolepsy spectrum disorders (NSDs). This study aimed to assess the prevalence of and factors associated with metabolic-syndrome-related disorders (MRDs) among patients with NSD. Japanese patients with NSD (NT1, n = 94; NT2, n = 83; and IH, n = 57) aged ≥35 years were enrolled in this cross-sectional study. MRD was defined as having at least one of the following conditions: hypertension, diabetes, or dyslipidemia. Demographic variables and MRD incidence were compared among patients in the respective NSD categories. Multivariate logistic regression analysis was used to investigate the factors associated with MRDs. Patients with NT1 had a higher body mass index (BMI) and incidence of MRD than that had by those with NT2 or IH. Age, BMI, and the presence of OSA were significantly associated with the incidence of MRD in NSDs. Age and BMI in NT1, BMI and human leukocyte antigen (HLA)-DQB1*06:02 positivity in NT2, and only age in IH were factors associated with the incidence of MRD. Obesity should be carefully monitored in narcolepsy; however, NT2 with HLA-DQB1*06:02 positive should be followed up for the development of MRD even without obesity.
言語 en
出版者
言語 en
出版者 MDPI
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
関連情報
識別子タイプ DOI
関連識別子 https://doi.org/10.3390/ijerph19106285
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 1661-7827
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 1660-4601
収録物名
言語 en
収録物名 International Journal of Environmental Research and Public Health
書誌情報
巻 19, 号 10, 発行日 2022-05-22
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